Duct-to-duct vs Roux-en-y Hepaticojejunostomy for Biliary Reconstruction in Adult Living Donor Liver Transplantation
NCT ID: NCT00646685
Last Updated: 2014-07-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
80 participants
INTERVENTIONAL
2008-02-29
2016-07-31
Brief Summary
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Detailed Description
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Biliary complications are much more common with right lobe living donor liver grafts than with whole organ grafts and are considered a major limitation of this surgery. Two surgical techniques are currently used for biliary reconstruction and each has its advantages/disadvantages. However, it is unclear which technique leads to fewer biliary complications. Retrospective studies which examine biliary complication rates may be hampered by such factors as a surgeon's bias or inexperience with a particular technique. Therefore a prospective randomized trial is needed.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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1
surgical technique: duct-to-duct biliary reconstruction
surgical reconstruction
2
surgical technique: roux-en-y biliary reconstruction
surgical reconstruction
Interventions
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surgical technique: duct-to-duct biliary reconstruction
surgical reconstruction
surgical technique: roux-en-y biliary reconstruction
surgical reconstruction
Eligibility Criteria
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Inclusion Criteria
* living donor liver transplantation using right hemi-liver as graft
* duct anastomosis possible at time of surgery
* donor and recipient aged 18 yrs or older
* written informed consent obtained
Exclusion Criteria
* acute fulminant liver failure
18 Years
90 Years
ALL
No
Sponsors
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University Health Network, Toronto
OTHER
Responsible Party
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Principal Investigators
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Markus Selzner, MD
Role: PRINCIPAL_INVESTIGATOR
University Health Network, Toronto
Locations
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Toronto General Hospital
Toronto, Ontario, Canada
Countries
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Other Identifiers
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07-0498-B
Identifier Type: -
Identifier Source: org_study_id
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