BIOSURE™ HEALICOIL™ PK Bone In-growth Study

NCT ID: NCT02382341

Last Updated: 2020-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

12 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-12

Study Completion Date

2017-01-04

Brief Summary

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The study seeks to document the bone in-growth into the BIOSURE™ HEALICOIL PK screw as measured by CT scans. Patients' improvement in pain and function will also be followed through various outcome measures.

Detailed Description

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The primary objective of the current study is to assess bone in-growth in the BIOSURE™ HEALICOIL™ Interference screw in the tibial tunnel of patients undergoing ACL reconstruction with soft tissue grafts; tunnel widening and change in IKDC knee and subjective scores will also be documented.

Conditions

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Deficiency of Anterior Cruciate Ligament

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational

BIOSURE™ HEALICOIL™ PK Interference Screw

BIOSURE™ HEALICOIL™ PK Interference Screw

Intervention Type DEVICE

Subjects will receive the appropriate sized BIOSURE™ HEALICOIL™ PK Interference Screw

Interventions

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BIOSURE™ HEALICOIL™ PK Interference Screw

Subjects will receive the appropriate sized BIOSURE™ HEALICOIL™ PK Interference Screw

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* ACL tear requiring surgical reconstruction with semitendinosus/gracilis graft.
* Willing and able to give voluntary informed consent to participate in this study
* Willing and able, in the opinion of the investigator, to cooperate with study procedures and willing to return to study site for all post-operative study visits.
* Subject is between 18 and 50 years at the time of surgery
* ASA group 0-2 (limited medical illness).

Exclusion Criteria

* Revision ACL reconstruction
* Cartilage injury (IKDC Grade IV lesion\> 2 cm2)
* Current malignant disease
* Rheumatoid arthritis
* Osteonecrosis or Avascular Necrosis
* Ankylosing spondylitis
* Subject is Obese; BMI \> 35
* Subject is pregnant or plans to become pregnant during the study
* Subject has received medical treatment within 6 weeks of enrollment with any of the following:

Glucocorticoids Growth hormone

* Participating in another investigational trial or on-going study that would interfere with the assessment of the primary and secondary outcomes
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Smith & Nephew, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Martin Lind, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Aarhus University Hospital

References

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Lind M, Nielsen T, Sorensen OG, Mygind-Klavsen B, Fauno P, Leake-Gardner S. Bone ingrowth into open architecture PEEK interference screw after ACL reconstruction. J Exp Orthop. 2020 Sep 18;7(1):68. doi: 10.1186/s40634-020-00285-z.

Reference Type DERIVED
PMID: 32948982 (View on PubMed)

Other Identifiers

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15000946

Identifier Type: -

Identifier Source: org_study_id

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