BIOSURE™ RG Knee Safety & Performance Study

NCT ID: NCT03519555

Last Updated: 2021-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-09

Study Completion Date

2020-10-05

Brief Summary

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Safety and Performance of the BIOSURE™ REGENESORB Interference Screw in Knee Ligament Repair and Reconstruction

Detailed Description

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This post-market clinical follow-up (PMCF) study will prospectively evaluate the short-term (6- and 12-month) safety and performance of the BIOSURE REGENESORB Interference Screw when used for any of the following:

Knee repair:

* ACL repair Posterior cruciate ligament (PCL) repair
* Extra-capsular repairs
* Medial collateral ligament (MCL)
* Lateral collateral ligament (LCL)
* Posterior oblique ligament (POL)
* Patellar realignment and tendon repairs
* Vastus medialis obliquus advancement
* Iliotibial band tenodesis

Conditions

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ACL Repair Posterior Cruciate Ligament (PCL) Repair Medial Collateral Ligament (MCL) Lateral Collateral Ligament (LCL) Posterior Oblique Ligament (POL) Patellar Realignment and Tendon Repairs Vastus Medialis Obliquus Advancement Iliotibial Band Tenodesis Extra-capsular Repairs Knee Repair

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Subject has provided informed consent for study participation.
2. Subject is eighteen (18) years of age or older at the time of enrollment in the study.
3. Subject requires one of the following knee procedures:

* Anterior cruciate ligament (ACL) repair
* Posterior cruciate ligament (PCL) repair
* Extra-capsular repair - Medial collateral ligament (MCL), Lateral collateral ligament (LCL), Posterior oblique ligament (POL)
* Patellar realignment and tendon repair Vastus medialis obliquus advancement Iliotibial band tenodesis
4. Subject is willing and able to comply with study visit schedule and to complete study procedures and questionnaires.

Exclusion Criteria

1. Subject has Body Mass Index (BMI) \> 40.
2. Subject has had total knee arthroplasty (TKA) in the study knee.
3. Subject has conditions that may interfere with graft survival or outcome (e.g. Paget disease, vascular insufficiency, muscular atrophy, uncontrolled diabetes, moderate to severe renal insufficiency or neuromuscular disease).
4. Subject has a known allergy to the study device or any of its components.
5. Subject, in the opinion of the Investigator, has an emotional or neurological condition that would pre-empt their willingness to participate in the study, including mental illness, mental retardation, drug or alcohol abuse, subject is pregnant, or plans to become pregnant during the study.
6. Subject is entered in another investigational drug, biologic, or device study, or has been treated with an investigational product in the past 30 days.
7. Subject is known to be at risk for loss to follow-up or failure to return for scheduled visits.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Smith & Nephew, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stephan Mangin

Role: STUDY_CHAIR

Smith & Nephew, Inc.

Locations

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OrthoIllinois

Rockford, Illinois, United States

Site Status

OrthoCarolina Research Institute, Inc.

Charlotte, North Carolina, United States

Site Status

Kelsey-Seybold Clinic/ Kelsey Research Foundation

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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16-5010-16

Identifier Type: -

Identifier Source: org_study_id

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