Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound

NCT ID: NCT04993339

Last Updated: 2021-09-05

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-24

Study Completion Date

2020-02-20

Brief Summary

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The goal of this study is to determine whether the use of injectable osteoinductive/osteoconductive compounds (OOC) during Anterior Cruciate Ligament (ACL) reconstructive surgery, combined with an accelerated rehabilitation protocol (ARP) provides clinical outcomes superior to those attained via traditional ACL reconstruction and delayed rehabilitation protocols.

Detailed Description

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Conditions

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ACL Injury

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Standard Surgery

Participants in this group undergoing standard of care reparative surgery will not receive additional intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Standard Surgery with OOC

Participants in this group undergoing standard of care reparative surgery will receive OOC as an additional intervention

Group Type EXPERIMENTAL

OOC

Intervention Type DRUG

The OOC will be mixed with autologous 5cc of platelet rich plasma (PRP), and then injected using a syringe into both tibia and femoral tunnels

Interventions

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OOC

The OOC will be mixed with autologous 5cc of platelet rich plasma (PRP), and then injected using a syringe into both tibia and femoral tunnels

Intervention Type DRUG

Other Intervention Names

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StimuBlast

Eligibility Criteria

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Inclusion Criteria

* any adult undergoing a surgical procedure for hamstring ACL reconstruction

Exclusion Criteria

* Adults unable to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Pregnant women
* Prisoners
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Arthrex, Inc.

INDUSTRY

Sponsor Role collaborator

University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Francesco Travascio

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Francesco Travascio

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Coral Gables, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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20150981

Identifier Type: -

Identifier Source: org_study_id

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