Serum MIF in Acute Kidney Injury

NCT ID: NCT02352506

Last Updated: 2023-03-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-31

Study Completion Date

2023-01-31

Brief Summary

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Acute kidney injury (AKI) is a common complication in critical care patients. Currently no parameters are available for early prognosis of AKI. Macrophage migration inhibitory factor (MIF) has been associated with AKI in clinical studies. The aim of this study is to evaluate the time course of MIF concentrations in patients with AKI.

Detailed Description

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Conditions

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Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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AKI

Patients developing AKI during the ICU stay

Blood draw for measurement of MIF

Intervention Type OTHER

Observational study, no intervention

No AKI

Matched controls not developing AKI during the ICU stay

Blood draw for measurement of MIF

Intervention Type OTHER

Observational study, no intervention

Interventions

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Blood draw for measurement of MIF

Observational study, no intervention

Intervention Type OTHER

Eligibility Criteria

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Exclusion Criteria

* Age \< 18 years and \> 80 years
* Patients with chronic dialysis
* Patients with continuous hemodialysis, hemofiltration or hemodiafiltration within 4 weeks prior to the study
* Patients with an expected length of ICU stay shorter than 3 days
* Patients with a low probability of surviving the first 2 days after ICU admission
* Pregnancy and nursing
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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David M Baron, MD, PhD

Univ.-Ass.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Medical University of Vienna

Vienna, , Austria

Site Status

Countries

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Austria

Other Identifiers

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1680/2014

Identifier Type: -

Identifier Source: org_study_id

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