Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-03-14

Brief Summary

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This study aims to test whether the addition of transcranial direct current stimulation (TDCS) to speech fluency training results in improvements in speech fluency in adults with developmental stuttering. Half of the participants will receive anodal TDCS on five consecutive days, the other half will receive a sham stimulation for the same amount of time.

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Detailed Description

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Studies using TDCS have shown improvements in motor performance, and in expressive language skills in clinical and healthy populations. The benefits of single sessions of TDCS are short-lived. However, stimulation over multiple sessions can increase and prolong learning effects that can persist for several weeks after the end of the stimulation period. We aim to target left hemisphere frontal regions involved in speech production with TDCS, and to pair this stimulation with speech fluency training.

Conditions

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Stuttering Fluency Disorders Speech Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Anodal TDCS

Participants will receive anodal TDCS over the left inferior frontal cortex. TDCS will be delivered at 1milliampere (mA) intensity for 20 minutes during speech fluency training (5 consecutive days).

Group Type EXPERIMENTAL

Anodal TDCS

Intervention Type DEVICE

20 minutes 1mA anodal stimulation to left inferior frontal cortex. Cathode positioned on right supra-orbital ridge.

Fluency Training

Intervention Type BEHAVIORAL

Speech tasks will be completed using fluency-enhancing techniques: metronome-timed speech and auditory choral speech.

Sham TDCS

Participants will receive sham TDCS over the left inferior frontal cortex. Sham stimulation will involve 30 seconds stimulation at the beginning of the 20 minutes of speech fluency training (5 consecutive days).

Group Type SHAM_COMPARATOR

Fluency Training

Intervention Type BEHAVIORAL

Speech tasks will be completed using fluency-enhancing techniques: metronome-timed speech and auditory choral speech.

Interventions

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Anodal TDCS

20 minutes 1mA anodal stimulation to left inferior frontal cortex. Cathode positioned on right supra-orbital ridge.

Intervention Type DEVICE

Fluency Training

Speech tasks will be completed using fluency-enhancing techniques: metronome-timed speech and auditory choral speech.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Native speaker of English.
* Right handed.
* Participant has moderate to severe Developmental Stuttering (Stammering)

Exclusion Criteria

* Speech, language or communication disorder other than Developmental Stuttering.
* Sensory impairment (hearing loss or visual impairment)
* History of drug abuse.
* History of seizures
* History of a neurological or psychiatric illness.
* History of neurosurgical procedure.
* Currently taking certain prescription medications such as anti-depressants and anti-malarial medication (as these may lower the seizure threshold)

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No