Investigating a Model for Acute Ischemic Pain in Humans

NCT ID: NCT02192242

Last Updated: 2014-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-06-30

Study Completion Date

2008-08-31

Brief Summary

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The pathophysiology of acute ischemic pain is not well established. The aim of the present study was to investigate acute ischemic pain in humans with a view to establish a scientific model to perform future studies. The investigators examined whether peripheral nerve damage and acute inflammation occur during short episodes of acute ischemia.

Detailed Description

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Conditions

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Peripheral Arterial Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Acute ischemic pain

acute ischemic pain was induced by treadmill testing in all patients investigated

Group Type EXPERIMENTAL

acute ischemic pain

Intervention Type OTHER

acute ischemic pain was induced by treadmill exercise

Interventions

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acute ischemic pain

acute ischemic pain was induced by treadmill exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients over 40 years
* unilateral femoral-popliteal PAD, Fontaine grade II

Exclusion Criteria

* patients with pain at rest or other pain origin
* diabetic polyneuropathy
* deep vein thrombosis
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ludwig-Maximilians - University of Munich

OTHER

Sponsor Role lead

Responsible Party

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Philip Lang

Attending physician, Assistant Professor of Anesthesiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Philip M Lang, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Anesthesiology, Ludwig-Maximilians-University Munich

Locations

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University Hospital Munich, Pettenkoferstr. 8a

Munich, , Germany

Site Status

Countries

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Germany

Other Identifiers

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001

Identifier Type: -

Identifier Source: org_study_id

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