Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
80 participants
OBSERVATIONAL
2008-10-31
2011-10-31
Brief Summary
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Detailed Description
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We hypothesis that patients with neuropathic pain has abnormal cortical excitability and plasticity in certain brain area. Therefore developed neuropathic pain certain diseased condition while others not. Therefore, we will use multimodal electrophysiology tools,such as transcranial magnetic stimulation, peripheral nerve stimulation, and contact heat evoke potential to monitor the cortical excitability and plasticity non-invasively.
Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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1
Healthy volunteers
No interventions assigned to this group
2
Patient with neuropathic pain
No interventions assigned to this group
3
patients without neuropathic pain
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* patients with pain resulted from dysfunction of peripheral or central nervous system
* the disorders of peripheral nerves are diagnosed by nerve conduction study, quantitative sensory test, quantification of skin innervation or contact heat evoked potentials
* lesion of central nervous system should be confirmed by neuroimage.
Exclusion Criteria
* previous brain surgery or intracranial metalic implant
* implanted devices as cardiac pacemaker
* pregnant subjects
* patient with severe cardiac or pulmonary disease who potentially cannot tolerate stress
20 Years
65 Years
ALL
Yes
Sponsors
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National Taiwan University Hospital
OTHER
Responsible Party
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National Taiwan University, Department of Neurology
Principal Investigators
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Ming-Kai Pan, M.D.
Role: STUDY_DIRECTOR
National Taiwan University Hospital, Department of Neurology
Chi-Chao Chao, M.D.
Role: STUDY_DIRECTOR
National Taiwan University Hospital, Department of Neurology
Sung-Tsang Hsieh, M.D. PhD
Role: PRINCIPAL_INVESTIGATOR
National Taiwan University Hospital, Department of Neurology
Locations
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National Taiwan University Hospital
Taipei, , Taiwan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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200806061R
Identifier Type: -
Identifier Source: org_study_id
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