Predicting Normal vs. Carrier Status in Euploid Embryos of Translocation Carriers

NCT ID: NCT02178865

Last Updated: 2017-03-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

11 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2017-02-28

Brief Summary

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The purpose of this study is to assess the accuracy of predicting the normal or carrier status of human embryos resulting from in vitro-fertilization (IVF) from patients carrying a balanced translocation.

Detailed Description

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This study aims to evaluate the validity of using informative SNPs to distinguish balanced from normal embryos. This will involve acquiring material from families to set phase for informative SNPs, evaluation of existing and new embryo SNP array data, and follow up analysis of children born after applying the procedure.

Conditions

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Balanced Chromosomal Translocation

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Study Groups

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translocation carrier

balanced translocation carriers who have undergone IVF

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with balanced translocations who have undergone IVF

Exclusion Criteria

* those who do not wish to know their child(s) karyotype
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Reproductive Medicine Associates of New Jersey

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Richard T Scott, MD, HCLD

Role: PRINCIPAL_INVESTIGATOR

Reproductive Medicine Associates of New Jersey

Locations

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Reproductive Medicine Associates of New Jersey

Basking Ridge, New Jersey, United States

Site Status

Countries

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United States

Other Identifiers

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RMA-2014-01

Identifier Type: -

Identifier Source: org_study_id

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