Can Brief High-intensity Interval Training Mitigate the Adverse Consequences of High-fat Overfeeding?
NCT ID: NCT02177604
Last Updated: 2018-05-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
7 participants
INTERVENTIONAL
2014-11-30
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Wingate HIT
7 days of high-fat overfeeding (50% excess calories) in conjunction 3 supervised sessions of Wingate High-intensity Interval Training.
Wingate HIT
3 sessions of Wingate based High-Intensity Interval Training (6-8 x 15 second "all out" sprints on a cycle ergometer interspersed by 2 minutes recovery)
High-fat overfeeding
7 days of high-fat overfeeding (50% excess calories)
Modified HIT
7 days of high-fat overfeeding (50% excess calories) in conjunction with 3 supervised sessions of Modified High-Intensity Interval Training
Modified HIT
3 sessions of Modified High-Intensity Interval Training (8 x 60 second sprints at approximately 90-95% VO2 peak on a cycle ergometer interspersed by 60 seconds recovery)
High-fat overfeeding
7 days of high-fat overfeeding (50% excess calories)
No Exercise Control
7 days of high-fat overfeeding (50% excess calories) with no supervised exercise
High-fat overfeeding
7 days of high-fat overfeeding (50% excess calories)
Interventions
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Wingate HIT
3 sessions of Wingate based High-Intensity Interval Training (6-8 x 15 second "all out" sprints on a cycle ergometer interspersed by 2 minutes recovery)
Modified HIT
3 sessions of Modified High-Intensity Interval Training (8 x 60 second sprints at approximately 90-95% VO2 peak on a cycle ergometer interspersed by 60 seconds recovery)
High-fat overfeeding
7 days of high-fat overfeeding (50% excess calories)
Eligibility Criteria
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Inclusion Criteria
* Overweight (BMI 25-29.9 kg/m2)
Exclusion Criteria
* History of chest pain (either at rest or during exercise.)
* Abnormal resting ECG at screening visit
* Chronic use of any prescribed or non-prescribed medications (i.e. anti-hypertensive, statins, metformin, anti-inflammatories, antidepressants etc.)
* Blood pressure or blood lipids outside of reference ranges
* Serum ferritin \<30ng/mL
* Uncontrolled asthma, current fever, or upper respiratory infection
* Current intake of \> 140g alcohol/week
* Current smokers of cigarettes/cigars/marijuana
* Current intake of any illicit substance
* Experience claustrophobia in confined spaces
* Donated blood in the past 3 months
* Migraines
* Unable to comprehend study protocol
* Unable to perform exercise on a cycle ergometer at second screening visit
18 Years
45 Years
MALE
Yes
Sponsors
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Royal Adelaide Hospital
OTHER
University of South Australia
OTHER
University of Adelaide
OTHER
Responsible Party
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A/Prof Leonie Heilbronn
Associate Professor
Principal Investigators
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Leonie Heilbronn, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Adelaide
Locations
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South Australian Health & Medical Research Institute
Adelaide, South Australia, Australia
Countries
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Other Identifiers
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140319
Identifier Type: -
Identifier Source: org_study_id
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