Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

220 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2016-02-29

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. Previous studies have reported that the incidence of AKI in patients undergoing surgery for congenital heart disease is as high as 42% and AKI increase the patient mortality, intensive care unit stay and hospital stay. Previous studies have reported several risk factors for AKI after congenital heart surgery, however, perioperative variables including anesthesia-related factors have not been evaluated fully. Therefore, the investigators attempt to find out independent risk factors regarding perioperative variables.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Thoracic Aortic Surgery

NCT01401218

Thoracic Aortic Surgery

COMPLETED

The Association Between the Duration of Acute Kidney Injury and New-onset Chronic Kidney Disease After Cardiac or Thoracic Aortic Surgery

NCT04172103

Acute Kidney Injury Chronic Kidney Disease, Stage 3 Chronic Kidney Disease, Stage 5 +2 more

COMPLETED

Predicting Acute Kidney Injury After Coronary Artery Bypass Graft

NCT02081261

Coronary Artery Bypass Surgery Acute Kidney Injury Creatinine +1 more

COMPLETED

A Predictive Score System for AKI Following Pediatric Cardiac Surgery

NCT05489263

Congenital Heart Disease Surgery--Complications Acute Kidney Injury

UNKNOWN

Hematologic Ratios in Postoperative Acute Kidney Injury

NCT03658148

Acute Kidney Injury

WITHDRAWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. Previous studies have reported that the incidence of AKI in patients undergoing surgery for congenital heart disease is as high as 42% and AKI increase the patient mortality, intensive care unit stay and hospital stay. Previous studies have reported several risk factors for AKI after congenital heart surgery, however, perioperative variables including anesthesia-related factors have not been evaluated fully. In addition, a neutrophil-lymphocyte ratio (NLR), which have been reported to be a marker for systemic inflammation and associated with prognosis of cardiac and cancer patients might be able to predict development of postoperative AKI. Therefore, the investigators attempt to assess independent risk factors regarding perioperative variables including transfusion-related parameters, preoperative anemia, preoperative hypoalbuminemia, pulmonary hypertension, use of nitric oxide, use of hydroxyethyl starch, perioperative medication, hemodynamic variables and perioperative NLR.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Patients Undergoing Surgery for Congenital Heart Disease

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

patients who underwent surgery for congenital heart disease

patients who underwent surgery for congenital heart disease during 2012 in Samsung Medical Center

surgery for congenital heart disease

Intervention Type PROCEDURE

surgery for congenital heart disease

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

surgery for congenital heart disease

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients who underwent surgery for congenital heart disease between January 2012 and December 2012 in Samsung Medical Center

Exclusion Criteria

* incomplete data for creatinine, estimated glomerular filtration rate, or urine output required to diagnose acute kidney injury
* patients who expired within 24 hours after surgery

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No