Acute Kidney Injury in Major Abdominal Surgery: Retrospective Study of 501 Patients

NCT ID: NCT04130347

Last Updated: 2019-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

499 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-01

Study Completion Date

2017-09-30

Brief Summary

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Retrospective study that aims to examine the presence of acute kidney injury (AKI) during major abdominal surgery, non- cardiac surgery. Using clinical and biochemical data in order to establish AKI frequency and risk factors.

Detailed Description

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Ethical approval was submitted and approved by the regional ethical committee, Etisk prövningsnämnd Uppsala, # 2017/418.

Patients were selected from the time span of april 2016 to september 2017. The investigators identified 499 patients that had undergone any of the selected procedures. The procedures were, pancreatic resection, HIPEC surgery in colorectal setting, gynecological debulking in metastasized ovarian cancer, and liver resection.

The risk of acute kidney injury (AKI) by the KDIGO definition during the postoperative period will be estimated in the group as a whole, and for each type of surgery separately. In addition the data will be stratified by sex to investigate systematic gender disparities or physiological differences. Length of stay, thirty day and sixty day mortality will secondary endpoints.

Conditions

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Acute Kidney Injury

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Pancreatic resection

No interventions assigned to this group

Liver resection

No interventions assigned to this group

HIPEC surgery

No interventions assigned to this group

Gynecological debulking surgery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Any of the selected procedures.

Exclusion Criteria

Patient has expressed his or her will to nor participate in any study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uppsala University

OTHER

Sponsor Role lead

Responsible Party

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Michael Hultström

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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EPN dnr 2017/218

Identifier Type: -

Identifier Source: org_study_id

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