AKIN Criteria: Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft (CABG)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

817 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-01-31

Study Completion Date

2008-01-31

Brief Summary

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The purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.

Detailed Description

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Eight hundred and seventeen patients was enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after on-pump CABG. Group AKI (+) - patients with acute kidney injury after on-pump CABG. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Clinical Outcomes and 30-day mortality was evaluate in this patients.

Conditions

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Kidney Failure

Keywords

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Acute Kidney failure Clinical outcomes On-pump Coronary artery bypass grafting Morbidity Mortality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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AKI (-)

Patients without acute kidney injury after on-pump CABG

No interventions assigned to this group

AKI (+)

Patients with acute kidney injury after on-pump CABG

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients underwent on-pump coronary artery bypass grafting
* Patients with at least two serum creatinine values within 48 hours.

Exclusion Criteria

* Patients with end-stage kidney disease requiring renal replacement therapy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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São José do Rio Preto Medical School

Principal Investigators

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Lilia N Maia, PhD

Role: STUDY_DIRECTOR

São José do Rio Preto Medical School

References

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Machado MN, Miranda RC, Takakura IT, Palmegiani E, Santos CA, Oliveira MA, Mouco OM, Hernandes ME, Lemos MA, Maia LN. Acute kidney injury after on-pump coronary artery bypass graft surgery. Arq Bras Cardiol. 2009 Sep;93(3):247-52. doi: 10.1590/s0066-782x2009000900008. English, Portuguese, Spanish.

Reference Type DERIVED

PMID: 19851652 (View on PubMed)

Other Identifiers

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CAAE-3438.0.000.140-08

Identifier Type: -

Identifier Source: org_study_id