MedDataX Logo

Predicting Acute Kidney Injury After Coronary Artery Bypass Graft

NCT ID: NCT02081261

Last Updated: 2016-06-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

877 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-02-29

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Acute kidney injury after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. There have been many studies reporting risk factor of acute kidney injury after cardiac surgery, but the influence of perioperative variables related to anesthesia and perioperative medication has not been evaluated fully. The investigators attempt to evaluate the influence of perioperative clinical variables including preoperative medication, preoperative albumin level, uric acid concentration, anesthesia technique, use of hydroxyethyl starch, blood glucose level, intraoperative medication, perioperative cardiac function (systolic and diastolic function) and hemodynamic variables during surgery on the incidence of acute kidney injury after coronary artery bypass graft.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Association Between the Duration of Acute Kidney Injury and New-onset Chronic Kidney Disease After Cardiac or Thoracic Aortic Surgery

NCT04172103

Acute Kidney Injury Chronic Kidney Disease, Stage 3 Chronic Kidney Disease, Stage 5 +2 more
COMPLETED

Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Thoracic Aortic Surgery

NCT01401218

Thoracic Aortic Surgery
COMPLETED

Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach

NCT01844219

Aortic Surgery Postoperative Acute Kidney Injury
COMPLETED

Cardiovascular Surgery Early Prediction System for AKI :CARDS-AKI Registry

NCT07330453

Cardiovascular Surgery
NOT_YET_RECRUITING

Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease

NCT02081235

Patients Undergoing Surgery for Congenital Heart Disease
COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Acute kidney injury (AKI) after cardiac surgery is a major complication after cardiac surgery and has been reported to be associated with adverse outcome. There have been many studies reporting risk factor of acute kidney injury after cardiac surgery, but the influence of perioperative variables related to anesthesia and perioperative medication has not been evaluated fully. The investigators attempt to evaluate the influence of preoperative medication, preoperative albumin level, uric acid concentration, NL ratio, anesthesia technique, use of hydroxyethyl starch, blood glucose level, intraoperative medication, perioperative cardiac function (systolic and diastolic) and hemodynamic variables during surgery on the incidence of acute kidney injury after coronary artery bypass graft. Preoperative and postoperative diastolic dysfunction may be associated with postoperative AKI. In addition, preoperative neutrophil-lymphocyte ratio (NLR) which has been reported to be a marked for systemic inflammation and was associated with prognosis in cardiac patients undergoing coronary artery bypass graft or percutaneous coronary intervention. This preoperative or immediate postoperative NLR might be able to predict AKI after coronary artery bypass surgery.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Artery Bypass Surgery Acute Kidney Injury Creatinine Mortality

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Coronary artery bypass surgery

patients who underwent coronary artery bypass surgery between 2010 and 2012 in Samsung Medical Center

Coronary artery bypass surgery

Intervention Type PROCEDURE

coronary artery bypass surgery

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Coronary artery bypass surgery

coronary artery bypass surgery

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients who underwent coronary artery bypass surgery during between 2010 and 2012 in Samsung Medical Center

Exclusion Criteria

* lack of postoperative creatinine or urine output data
* patients who expired within 24hours after surgery
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

WonHo Kim

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

Review the countries where the study has at least one active or historical site.

South Korea

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2013-12-116

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine
NCT06772025 RECRUITING NA
Biomarkers of Acute Kidney Injury in Cardiac Surgery
NCT03830450 UNKNOWN
The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery
NCT02496234 COMPLETED
A Clinical Score to Predict Acute Kidney Injury After Heart Valve Replacement Surgery
NCT04237636 COMPLETED
Acute Kidney Injury After Cardiac Surgery Based on KDIGO Criteria
NCT00777465 COMPLETED
AKIN Criteria: Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft (CABG)
NCT00780845 COMPLETED
Machine Learning Predict Acute Kidney Injury in Patients Following Cardiac Surgery
NCT04966598 COMPLETED
Incidence and Risk Factors of Acute Kidney Injury After Thoracic Aortic Surgery Due to Dissection
NCT02190487 COMPLETED
RRI Compared With NephroCheckTM to Predict Acute Renal Failure After Cardiac Surgery.
NCT02325726 COMPLETED
Acute Kidney Injury After Cardiac Surgery
NCT05079724 UNKNOWN
Machine Learning Predict Renal Replacement Therapy After Cardiac Surgery
NCT04977687 COMPLETED
Biomarkers of Acute Kidney Injury Following Cardiac Surgery
NCT04387149 UNKNOWN
Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)
NCT02838667 COMPLETED NA
Acute Post-cardiac Surgery Renal Failure: Prevention Through Individualized Intensive Hemodynamic Management
NCT04005105 COMPLETED NA
Cardiac Anesthesia Registry Including Biosignal Database for Prognostication of Postoperative Renal Outcome
NCT06581289 NOT_YET_RECRUITING
Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers
NCT06351813 NOT_YET_RECRUITING
Association Between Renal Resistive Index(RRI) and AKI(Acute Kidney Injury) in Cardiac Surgery Patients With Cardiopulmonary Bypass (CPB)
NCT06464666 NOT_YET_RECRUITING
Early RRT in AKI After Cardiac Surgery
NCT05175053 RECRUITING NA
Acute Kidney Injury Following Cardiac Surgery
NCT03102528 COMPLETED
Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery
NCT00774137 COMPLETED
Prevention of Acute Kidney Injury in Cardiac Surgery Patients
NCT00921518 COMPLETED PHASE2
Association Between Liver Function Tests and Acute Kidney Injury in Cardiac Surgery Patients
NCT06730854 COMPLETED
Artificial Intelligence and Postoperative Acute Kidney Injury
NCT04705064 UNKNOWN
A Machine Learning Prediction Model for Postoperative Acute Kidney Injury in Non-Cardiac Surgery Patients
NCT07030166 RECRUITING
Acute Kidney Injury After Cardiac Surgery
NCT03457987 COMPLETED