Risk Factors for Acute Kidney Injury in Patients Undergoing Arthroplasty

NCT ID: NCT06296108

Last Updated: 2024-03-06

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 911 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-06-01
• Study Completion Date: 2022-12-31

Brief Summary

The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.

Detailed Description

Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications.

Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.

Conditions

Postoperative Acute Kidney Injury; Arthroplasty

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Interventions

acute kidney injury

The incidence of acute kidney injury was determined in patients included to the study

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients aged above 18 years old undergoing arthroplasty surgery

Exclusion Criteria

• Known acute renal failure or chronic renal failure
• Patients aged below 18 years old
• Patients refusing to participate to the study

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ankara University

OTHER

Sponsor Role: lead

Responsible Party

Sanem Cakar Turhan

Associate professor, MD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Sanem Çakar Turhan, Assoc. Prof.

Role: STUDY_CHAIR

Ankara University Medical School, Department of Anesthesiology and ICU

Hazal Nur Tezel Kılıc, Specialist

Role: PRINCIPAL_INVESTIGATOR

Ankara University Medical School, Department of Anesthesiology and ICU

Suheyla Karadag Erkoc, Assoc. Prof.

Role: PRINCIPAL_INVESTIGATOR

Ankara University Medical School, Department of Anesthesiology and ICU

Hakan Kocaoglu, Assoc. Prof.

Role: PRINCIPAL_INVESTIGATOR

Ankara University Medical School, Department of Orthopedics and Traumatology Surgery

Locations

Ankara University Medical School Anesthesiology and ICU Department

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

I05-310-22

Identifier Type: -

Identifier Source: org_study_id