Blood Products in Cardiac Surgery

NCT ID: NCT02068755

Last Updated: 2014-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

31000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-01-31

Study Completion Date

2012-12-31

Brief Summary

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Blood transfusion is a common procedure essential for the treatment of patients undergoing cardiac surgery. Inappropriate transfusions, however, not only incur needless healthcare costs, but increase unnecessary risks due to transfusion reactions and infectious and immunomodulative causes. Safe and appropriate patient care requires evaluated blood component prescription practices.

Practically all patients undergoing cardiac surgery in Finland have a blood product booking from the Finnish Red Cross Blood Service. This registry contains large volumes of transfusion-related information on all Finnish patients undergoing cardiac surgery in Finnish centers. Participating hospitals were scattered to all geographical areas in Finland and concentrated to the most populated regions.

Data on the blood product use, laboratory findings one month pre-operatively and 12 months post-operatively were available.

Finnish hospitals have been required to provide information on hospital visits for the Finnish National Research and Development Centre for Welfare and Health for healthcare planning purposes. We used in part the original data sent by hospitals to the Finnish Hospital Discharge Register (FHDR).

Detailed Description

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Registry includes

* \>21 000 patients who underwent coronary bypass,
* \>4500 patients with aortic valve replacement,
* \>4000 mitral valve operation.

Conditions

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Anemia Renal Impairment Thrombocytopenia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cardiac surgery

Patients who have undergone cardiac surgery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Cardiac surgery performed in Finnish University and Central hospitals
* Blood product booking for surgery

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Finnish Red Cross Blood Service

OTHER

Sponsor Role collaborator

Central Finland Hospital District

OTHER

Sponsor Role collaborator

Turku University Hospital

OTHER_GOV

Sponsor Role collaborator

Oulu University Hospital

OTHER

Sponsor Role collaborator

Tampere University Hospital

OTHER

Sponsor Role collaborator

Kuopio University Hospital

OTHER

Sponsor Role collaborator

Helsinki University Central Hospital

OTHER

Sponsor Role collaborator

Satakunta Central Hospital

OTHER

Sponsor Role collaborator

University of Turku

OTHER

Sponsor Role lead

Responsible Party

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Dr. Pirjo Mustonen, MD, PhD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pirjo Mustonen, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Central Finland Central Hospital

Juhani Airaksinen, Prof

Role: PRINCIPAL_INVESTIGATOR

Turku University Hospital and University of Turku

Fausto Biancari, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Oulu University Hospital

Tuomas O Kiviniemi, Md, PhD

Role: PRINCIPAL_INVESTIGATOR

Turku University Hospital and University of Turku

Other Identifiers

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BiCS

Identifier Type: -

Identifier Source: org_study_id

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