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The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study

NCT ID: NCT01067638

Last Updated: 2010-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-11-30

Study Completion Date

2010-09-30

Brief Summary

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The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.

Detailed Description

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Conditions

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Coronary Artery Occlusive Disease

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Study Groups

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tranexamic acid

Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft

Group Type EXPERIMENTAL

Tranexamic Acid

Intervention Type DRUG

1.0g loading dose before skin incision and continuous infusion 200 mg/h during surgery

Interventions

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Tranexamic Acid

1.0g loading dose before skin incision and continuous infusion 200 mg/h during surgery

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Fifty patients undergoing OPCAB with preoperative hematocrit levels lower than 35%

Exclusion Criteria

Patient who has

* Open heart surgery history before
* Thrombosis history
* Myocardial infarction (MI) within 7days recently
* Liver or Kidney disease
* been scheduled emergency surgery
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Severance Hospital, Dept. of Anesthesiology & Pain Medicine

Locations

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Yonsei Univ.

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2009-0488

Identifier Type: -

Identifier Source: org_study_id