NeoThyr - the Role of Mitochondria-dysfunction in Newborns of Mothers With Autoimmune Thyroid Disease
NCT ID: NCT02061111
Last Updated: 2023-04-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
77 participants
OBSERVATIONAL
2014-01-31
2021-10-31
Brief Summary
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The hypothesis of this study is that the offspring of women with subclinical thyroid disease have a mitochondria-dysfunction which leads to more complications during birth, poorer health and well-being in the early childhood. The investigators will test this by recruiting mothers by a blood sample in the third trimester of pregnancy, screen the cord blood at birth and later on test the children with Bayley test two times in the early childhood.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Subclinical thyroid disease
26 pregnant women with subclinical hypothyroidism and/orTPO-antibodies, and their offspring.
No interventions assigned to this group
Healthy controls
51 pregnant women without thyroid disease or any other metabolic disorders, and their offspring.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
50 Years
FEMALE
No
Sponsors
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University of Southern Denmark
OTHER
Region Zealand
OTHER
Naestved Hospital
OTHER
Responsible Party
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Julie K. G. Stryhn
MD
Principal Investigators
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Julie Stryhn, MD
Role: PRINCIPAL_INVESTIGATOR
Naestved Hospital
Peter Gæde, MD
Role: STUDY_CHAIR
Slagelse Hospital
Locations
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Gynaecologic-Obstetrics Department Naestved Hospital
Næstved, , Denmark
Countries
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Other Identifiers
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SJ-361
Identifier Type: -
Identifier Source: org_study_id
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