Proteomics in Multiple Trauma to Identify Organ Failure

NCT ID: NCT02030327

Last Updated: 2022-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

85 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2022-12-31

Brief Summary

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To analyse differences in protein expression in multiple trauma patients for identification of potential biomarkers to predict organ dysfunction.

Detailed Description

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The aim of the present study in humans is to analyse differences in protein expression after multiple trauma in patients for identification of potential biomarkers to predict organ dysfunction.

Conditions

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Multiple Trauma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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No trauma

n=5 patients

No interventions assigned to this group

trauma without organ dysfunction

n=40 patients

No interventions assigned to this group

trauma with organ dysfunction

n=40 patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* older than 18 years
* multiple trauma patients
* ISS \>16

Exclusion Criteria

* children
* ISS \<16
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universitätsklinikum Köln

OTHER

Sponsor Role lead

Responsible Party

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Jochen Hinkelbein

Priv.-Doz. Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jochen Hinkelbein, MD

Role: PRINCIPAL_INVESTIGATOR

UK Köln

Locations

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University Hospital of Cologne

Cologne, North Rhine-Westphalia, Germany

Site Status RECRUITING

Countries

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Germany

Facility Contacts

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Jochen Hinkelbein, MD

Role: primary

+49221478 ext. -97728

Other Identifiers

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12-236

Identifier Type: -

Identifier Source: org_study_id

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