Quantification of Transition Metals

NCT ID: NCT02222779

Last Updated: 2014-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Brief Summary

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In this trial, concentrations of transition metals of interest are quantified in surplus cerebrospinal fluid (CSF) and blood serum samples. Quantification of the transition metals will be performed by inductively coupled plasma mass spectrometry (ICP-MS). The treating physicians as well as the patients will not be informed about the results of drug concentrations.

Detailed Description

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Samples used include:

Remaining portions of samples collected for diagnostic or therapeutic reasons (paired CSF and blood serum samples). No lumbar puncture will be done specifically for this protocol.

The objective of this study is to gain an overview about transition metals concentrations in blood serum and CSF in order to provide preliminary data on patients. The effect of neurodegenerative diseases on metals or the other way round will be assessed if possible.

Conditions

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Neurodegenerative Diseases Infections

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Groups

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Patients with Parkinson´s Disease

No interventions assigned to this group

Patient´s with Alzheimer´s Disease

No interventions assigned to this group

Patients with Multiple Sclerosis

No interventions assigned to this group

Patients with any other neurodegenerative diseases

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* The trial will include any patient (with various diseases, especially neurodegenerative diseases) who received a lumbar puncture.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Cologne

OTHER

Sponsor Role lead

Responsible Party

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Ali Mohammad Nejad Sigaroudi

Quantification of Transition Metals in Patients at the Cologne University Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Pharmacology

Cologne, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

Central Contacts

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Uwe Fuhr, Professor

Role: CONTACT

0049221478 ext. 5230

Facility Contacts

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Uwe Fuhr, Professor

Role: primary

0049221478 ext. 5230

Other Identifiers

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KPUK-14-Metal

Identifier Type: -

Identifier Source: org_study_id

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