Implantation Rate of Vitrified-warmed Collapsed Blastocysts
NCT ID: NCT01980225
Last Updated: 2015-06-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
270 participants
INTERVENTIONAL
2011-11-30
2014-08-31
Brief Summary
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The aim of the study is to investigate the effect of artificial shrinkage by laser-induced collapse on the implantation potential of vitrified-warmed day 5 or day 6 blastocyst stage embryos in a prospective randomised controlled trial.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Collapse
This arm includes the patients where laser-induced collapse (=artificial shrinkage) of all blastocysts is performed before vitrification
Collapse
inducing collapse (= artificial shrinkage) by applying 1 or 2 laser pulses between trophectoderm cells of the blastocyst to be vitrified
control
This control arm includes the patients of which the blastocysts are vitrified without performing collapse
No interventions assigned to this group
Interventions
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Collapse
inducing collapse (= artificial shrinkage) by applying 1 or 2 laser pulses between trophectoderm cells of the blastocyst to be vitrified
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* at least 1 blastocyst available for cryopreservation
Exclusion Criteria
* IVM (in-vitro maturation) cycles
* PGD cycles (preimplantation genetic diagnosis)
18 Years
38 Years
FEMALE
Yes
Sponsors
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Centre for Reproductive Medicine, Belgium
OTHER
Responsible Party
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Lisbet Van Landuyt
klinisch embryoloog
Principal Investigators
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Lisbet Van Landuyt, MSc
Role: PRINCIPAL_INVESTIGATOR
Centre for Reproductive Medicine
Locations
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Centre for Reproductive Medicine
Brussels, , Belgium
Countries
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References
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Van Landuyt L, Polyzos NP, De Munck N, Blockeel C, Van de Velde H, Verheyen G. A prospective randomized controlled trial investigating the effect of artificial shrinkage (collapse) on the implantation potential of vitrified blastocysts. Hum Reprod. 2015 Nov;30(11):2509-18. doi: 10.1093/humrep/dev218. Epub 2015 Sep 12.
Other Identifiers
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VanLanduyt2013
Identifier Type: -
Identifier Source: org_study_id
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