Real-time Comparison of Left Ventricular Strokevolume Measurement by Four Different Methods

NCT ID: NCT01791283

Last Updated: 2013-02-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-08-31

Study Completion Date

2013-02-28

Brief Summary

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Real-time comparison of three different bedside strokevolumemeasurements (arterial waveform analysis, eosofageal doppler and 2D transthoracal ultrasound) validated against cardiac magnetic resonance imaging (CMRI)

Detailed Description

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20 healthy volounteers between age of 20-40 years, no previous medical history undergo simoultaneous left ventrikular strokevolume measurements using three different methods at rest. After datasampling and without moving, the subject then undergo Cardiac Magnetic Resonance Imaging with 2D-throughplane and cine tecnology for validation of volume measurements. The data is then analyzed using Bland-Altman calculation.

Conditions

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Difference in Measured Results Using Four Different Strokevolume Measurements Simultaneously.

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy volunteers

Healthy volounteers with no previous medical history, age between 20-40. Both male and female. Subjects are provided extensive information about the study and the obligations and expectations included. All subjects sign a witnessed informed consent before inclusion.

Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.

Intervention Type PROCEDURE

Interventions

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Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.

Intervention Type PROCEDURE

Other Intervention Names

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Vigileo/FloTrac, Edward Lifesciences (arterial waveform analysis) CardioQ, Deltex medical (esofageal doppler) Philips, Magnetic Resonance Imaging Vivid S6, GE, Cardiac ultrasound

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

* Heart and/or vascular disease such as angina pectoris, arrythmias, claudicatio intermittens e g.
* Diseases in gastrointestinal tract or nose.
* Coagulopathies
* Pregnancy
* Allergys for local anaesthetics
* Claustrofobia
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Linkoeping

OTHER

Sponsor Role lead

Responsible Party

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Anna Oscarsson

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Goran Liffner, MD

Role: PRINCIPAL_INVESTIGATOR

Intensivvardskliniken, Linkoping University Hospital

Locations

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Departement for intensive care medicine, Universitetssjukhuset

Linköping, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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FourCompv1

Identifier Type: -

Identifier Source: org_study_id

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