Pain on Injection of Propofol: a Comparison of Lidocaine and Alkalinized Lidocaine
NCT ID: NCT01773044
Last Updated: 2013-01-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
300 participants
INTERVENTIONAL
2012-09-30
2012-11-30
Brief Summary
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Methods: In this double-blind, placebo controlled study, 300 adults patients ASA I or II, scheduled to undergo elective surgery, were randomly assigned into three groups of 100 each. Group L, recevied 0.05 mL/kg lidocaine (% 2 lidocaine 5 mL + 5 mL SF), Group A, 0.05 mL/kg lidocaine with bicarbonate ( % 2 lidocaine 5 mL + 1 mL %8,4 NaHCO3+ 4 mL SF) and control group received isotonic saline pretreatment in the dorsum of the hand, followed by propofol 30 sec later. A blinded researcher assessed the patient's pain level via a four-point scale.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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alkalinized lidocaine & lidocaine
alkalinized lidocaine
recevied 0.05 mL/kg lidocaine with bicarbonate ( % 2 lidocaine 5 mL + 1 mL %8,4 NaHCO3+ 4 mL SF)
Lidocaine
0.05 mL/kg lidocaine (% 2 lidocaine 5 mL + 5 mL SF),
alkalinized lidocaine &Placebo
alkalinized lidocaine
recevied 0.05 mL/kg lidocaine with bicarbonate ( % 2 lidocaine 5 mL + 1 mL %8,4 NaHCO3+ 4 mL SF)
Placebo (for alcalinized lidocaine)
Interventions
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alkalinized lidocaine
recevied 0.05 mL/kg lidocaine with bicarbonate ( % 2 lidocaine 5 mL + 1 mL %8,4 NaHCO3+ 4 mL SF)
Lidocaine
0.05 mL/kg lidocaine (% 2 lidocaine 5 mL + 5 mL SF),
Placebo (for alcalinized lidocaine)
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
65 Years
ALL
Yes
Sponsors
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Inonu University
OTHER
Responsible Party
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Ülkü Özgül
department of anesthesiology
Locations
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Inonu university medicine faculty
Malatya, , Turkey (Türkiye)
Countries
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References
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Borazan H, Erdem TB, Kececioglu M, Otelcioglu S. Prevention of pain on injection of propofol: a comparison of lidocaine with different doses of paracetamol. Eur J Anaesthesiol. 2010 Mar;27(3):253-7. doi: 10.1097/EJA.0b013e328330eca2.
Other Identifiers
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ulkü_1
Identifier Type: -
Identifier Source: org_study_id
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