Prevention of Postoperative Atrial Fibrillation

NCT ID: NCT01742039

Last Updated: 2023-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-07-31

Study Completion Date

2011-06-30

Brief Summary

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The primary aim of this study is to determine the safest and most effective therapeutic strategy to decrease the incidence of postoperative atrial fibrillation following cardiac surgery in an era with shorter ICU and hospital length of stay. A secondary goal is to evaluate the length of hospital stay associated with each treatment strategy.

Detailed Description

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Conditions

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Postoperative Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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b-blocker

No interventions assigned to this group

amiodarone

No interventions assigned to this group

atrial pacing

No interventions assigned to this group

amiodarone plus atrial pacing

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age \> or = to 18 years
* sinus rhythm
* undergoing either coronary artery bypass graft surgery (CABG), valvular heart surgery or a combined procedure

Exclusion Criteria

* received a class-I or class-III antiarrhythmic agent in the past six months
* had second or third degree heart block
* had a resting heart rate of less than 50 beats per minute
* had a systolic blood pressure less than 100 mmHg
* had severe asthma or severe chronic obstructive pulmonary disease
* had uncontrolled heart failure
* had a serum aspartate aminotransferase or alanine aminotransferase concentration greater than four times the upper limit of normal
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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George Washington University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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George Washington University Hospital

Washington D.C., District of Columbia, United States

Site Status

George Washington University

Washington D.C., District of Columbia, United States

Site Status

Countries

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United States

Other Identifiers

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AF01

Identifier Type: -

Identifier Source: org_study_id

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