Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

NCT ID: NCT04880265

Last Updated: 2025-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-14

Study Completion Date

2030-05-31

Brief Summary

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Background and Significance:

In the United States approximately 220,000 patients undergo cardiac surgery per annum. Among potential complications, the incidence of atrial fibrillation (AF) is estimated at 30 - 60 %, and therefore presents the most common adverse event after cardiac surgery. Multiple complications may be associated with AF: Patients are usually subject to an increased length-of-stay in the intensive care unit and in the hospital. Furthermore, the risk for stroke and development of long-term AF is elevated, while further anticoagulation is required putting the patient at risk for bleeding. On average, an additional $10,000 - $20,000 is spent for each patient with AF. However, the exact burden of postoperative AF still remains unknown.

Specific Aims of Research Project:

1. To collect data from an electrocardiogram (EKG) monitoring patch, we aim to accurately determine the prevalence of atrial fibrillation in patients undergoing cardiac surgery at our center.
2. To collect data on epidemiological characteristics to investigate risk factors for developing perioperative atrial fibrillation in patients undergoing cardiac surgery. This will allow us to create robust risk prediction models.

Detailed Description

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Conditions

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Atrial Fibrillation Cardiac Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients undergoing cardiac surgery

Vivalink wearable life sensors

Intervention Type DEVICE

Collection of EKG data

Interventions

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Vivalink wearable life sensors

Collection of EKG data

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Elective open heart surgery
* Age \> 20 years

Exclusion Criteria

* Refusal to participate (patient or health care proxy)
* Participation in other pharmacological trials
* Lack of data or poor data quality which cannot be analyzed for any heart rhythm in 80% of the postoperative study period.
Minimum Eligible Age

20 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Brigham and Women's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jakob Wollborn, MD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jakob Wollborn, MD MPH

Role: CONTACT

6175258156

Facility Contacts

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Jochen D Muehlschlegel, MD, MMSc

Role: primary

617-732-7330

Other Identifiers

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2021P000356

Identifier Type: -

Identifier Source: org_study_id

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