Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-01-31

Brief Summary

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Acute changes in axial diffusivity will correlate with the severity of injury in patients that suffer an acute spinal cord injury.

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Detailed Description

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Diffusion tensor imaging (DTI) parameters will correlate with severity of spinal cord injury in SCI patients as seen in rodent models. We will test whether the quantitative decrease in axial (λ║) diffusivity (a biomarker of axonal injury), will predict long-term functional outcomes for patients with a SCI.

Specific Aim: To examine patients after an acute SCI using DTI and to correlate the extent of acute decrease in λ║ with the presenting ASIA motor score and long-term functional outcome of the patient.

Conditions

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Cervical Spinal Cord Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cervical spinal cord injury

Those patients with an acute cervical spinal cord injury evaluated with DTI MRI

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18-65 years of age
* Cervical spinal cord injury
* physically and mentally willing to comply with imaging
* lives in immediate area with no plans to relocate