Development and Evaluation of a New Diagnostic Test in Female Urinary Stress Incontinence

NCT ID: NCT01563653

Last Updated: 2017-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-20

Study Completion Date

2017-02-23

Brief Summary

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The investigators hypothesize that an innovative test device simulating transvaginal tape support will increase the performance and reproducibility of the diagnosis of urethral hypermobility before surgery for urinary incontinence.

The main objective of this study is to compare two prognostic tests in their ability to predict the success (or failure) of the implementation of a suburethral TVT (tension-free vaginal tape) or TOT (trans-obturator tape) treatment for stress urinary incontinence in women. The Q-tip test (test mentioned in the French and international recommendations) is compared to test a new test (clip strip).

Detailed Description

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Secondary objectives include:

* Compare the prognostic ability of the clip strip test with the Bonney maneuver
* Compare the prognostic ability of the clip strip test with the TVT maneuver
* Compare the maximum intraurethral pressure during various tests
* Compare the quality of life before / after surgery
* Estimate patient satisfaction one year after surgery
* Describe the intra and inter-operator reproducibility of various prognostic tests.
* Estimate the optimal threshold of the Q-tip angle based on surgical results and compare with the reference threshold of 30 ° found in the literature.

Conditions

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Urinary Incontinence, Stress

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Patients

Women with stress urinary incontinence schelduled for TVT or TOT procedures. See inclusion/exclusion criteria.

Group Type EXPERIMENTAL

4 diagnostic tests for surgical success

Intervention Type PROCEDURE

Q-tip test, Bonney maneuver, TVT maneuver, clip strip test

Interventions

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4 diagnostic tests for surgical success

Q-tip test, Bonney maneuver, TVT maneuver, clip strip test

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The patient must have given his/her informed and signed consent
* The patient must be insured or beneficiary of a health insurance plan
* The patient is available for 60 weeks of follow-up
* Candidate for stress urinary incontinence surgery by TVT or TOT procedures
* Positive cough or valsalve maneuver test

Exclusion Criteria

* The patient is participating in another study (except the PISQ-R study)
* The patient is in an exclusion period determined by a previous study
* The patient is under judicial protection, under tutorship or curatorship
* The patient refuses to sign the consent
* It is impossible to correctly inform the patient
* The patient is pregnant, parturient, or breastfeeding
* The patient has a contra-indication for stress urinary incontinence surgery via TVT or TOT procedures.
* The patient has an untreated vaginal or urniary infection
* The patient has a history of allergy to polyurethane and / or Watershed XCX11122
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Renaud de Tayrac, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire de Nîmes

Locations

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CHU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, Gard, France

Site Status

CH de Dignes les Bains

Digne-les-Bains, , France

Site Status

Countries

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France

Other Identifiers

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2011-A01225-36

Identifier Type: OTHER

Identifier Source: secondary_id

LOCAL/2011/RdeT-01

Identifier Type: -

Identifier Source: org_study_id

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