Treatment of Female Stress Urinary Incontinence: Study Comparing Two Suburethral Slings, Retropubic Approach (TVT) and Trans-Obturator (TVT-O) Approach

NCT ID: NCT00135616

Last Updated: 2007-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-03-31

Study Completion Date

2008-03-31

Brief Summary

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The purpose of this study is to compare efficacy and morbidity following the placement of two types of suburethral slings in women presenting with stress urinary incontinence: TVT and TVT-O.

Detailed Description

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Urinary stress incontinence (USI) is a frequent pathology in women. Surgical treatment is required in 30 to 50% of women presenting with USI. Several surgical techniques are currently available.

At the present time, the placement of suburethral slings is one of the most efficient techniques. Furthermore, the placement of a suburethral sling is known to be associated with a low rate of complications.

Currently, two approaches are available for the placement of a suburethral sling: retropubic approach (TVT) and trans-obturator approach (TVT-O). The efficacy of these two approaches seem equivalents. However, the morbidity related to these two techniques is probably different. In retrospective studies, the retropubic approach is associated with a higher rate of bladder perforation. On the other hand, the trans-obturator approach is supposed to be associated with a higher rate of post-operative pain.

Thus, the purpose of this study is to compare efficacy and morbidity following the placement of two types of suburethral slings in women presenting with stress urinary incontinence: TVT and TVT-O.

Conditions

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Urinary Incontinence, Stress

Keywords

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urinary incontinence stress incontinence urethra gynaecologic surgical procedures suburethral sling

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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surgical placement of a suburethral sling tvt or tvt-o

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Woman over 18 years old
* Clinical diagnosis of stress urinary incontinence requiring surgical management
* Must be able to read and sign the consent

Exclusion Criteria

* Pregnancy
* Anti-coagulant treatment
* Isolated overactive bladder syndrome
* Genital prolapse requiring surgical treatment
* Concomitant hysterectomy
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hopital Antoine Beclere

OTHER

Sponsor Role lead

Principal Investigators

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Xavier Deffieux, MD

Role: PRINCIPAL_INVESTIGATOR

Hopital Antoine Beclere, Clamart, France

Locations

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CHU Amiens

Amiens, , France

Site Status

Centre Hospitalier Universitaire

Angers, , France

Site Status

CHU Pellegrin

Bordeaux, , France

Site Status

Hopital Saint Andre

Bordeaux, , France

Site Status

CH Chambery

Chambéry, , France

Site Status

Hopital Antoine Beclere

Clamart, , France

Site Status

Hôtel Dieu

Clermont-Ferrand, , France

Site Status

CH Dunkerque

Dunkirk, , France

Site Status

Centre Hospitalier Paul Ardier

Issoire, , France

Site Status

Chu Nancy

Nancy, , France

Site Status

CH Caremeau

Nîmes, , France

Site Status

Hopital Diaconesses Croix Saint Simon

Paris, , France

Site Status

CH Rennes

Rennes, , France

Site Status

CH Rouen

Rouen, , France

Site Status

Countries

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France

Other Identifiers

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xd01

Identifier Type: -

Identifier Source: org_study_id