Medico-economic Evaluation of Subcutaneous Automatic Resorbable Staples Device

NCT ID: NCT01546272

Last Updated: 2016-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

664 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-03-31

Study Completion Date

2015-11-30

Brief Summary

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A surgery made by an external incision requires to stitch the subcutaneous plans, usually performed using absorbable synthetic sutures hold on wire needle. This national, prospective, multicentric, and randomized study is devoted to estimate a technique of suture of the subcutaneous plans based on an implantable medical device delivering automatically absorbable staples. This particularly innovative technique lets to expect a tolerance and an efficiency at least equivalent to the reference technique (main objective). Moreover, this technique allows to anticipate a reduction of the duration of surgical procedure and anesthetic time while limiting the risks of blood wounds of the medical staff.The medical economic part of this study will check, from the point of view of the health care hospital, wether the technique is likely to reduce the costs and time consuming theater room procedures.

Detailed Description

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Conditions

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ENT Surgery Gynecological Surgery Plastic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Resorbable staples

Suture using Insorb Resorbable staples

Group Type EXPERIMENTAL

Insorb resorbable staples

Intervention Type DEVICE

Subcutanous suture using resorbable staples

Resorbable wires

Suture using Monocryl resorbable wire

Group Type ACTIVE_COMPARATOR

Monocryl resorbable wire

Intervention Type DEVICE

Subcutanous suture using resorbable wire

Interventions

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Insorb resorbable staples

Subcutanous suture using resorbable staples

Intervention Type DEVICE

Monocryl resorbable wire

Subcutanous suture using resorbable wire

Intervention Type DEVICE

Other Intervention Names

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Insorb staples Monocryl Wire

Eligibility Criteria

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Inclusion Criteria

* Male or female aged 18 yrs to 75 yrs
* Patient supported for a scheduled surgery :

For abdominoplasty, cervicotomy or suprapubic surgery With a open incision necessary for operative exposition of 10 cm or more with a straight or curved surgery incision

* Person covered by Health Insurance
* ECOG Performance Status 0 or 1
* Patient's informed and written consent

Exclusion Criteria

* Incision imposing a very angular or sinuous scar for which the use of the medical device is deemed unsuited (sinuous or bayonet incisions)
* Known history of intolerance to any component of the medical device
* Immunocompromised patients or undergoing a long term treatment by corticosteroids or immunosuppressants
* Known or anticipated presence of a skin infection (due to the infected skin condition, or because of underlying surgery conducted in infected territory or likely to be)
* Dermatological disease or skin treatment in progress
* History of radiation therapy on the surgical site or antimitotic treatment in progress
* Pregnancy at the time of suture
* Patients simultaneously included in another treatment protocol
* Patients under legal guardianship
* Non French speaking patients, refusing or unfit for the monitoring proposed in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nantes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Olivier Malard, Professor

Role: PRINCIPAL_INVESTIGATOR

Nantes University Hospital

Locations

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CHU de Nantes

Nantes, Pays de la Loire Region, France

Site Status

Amiens University Hospital

Amiens, , France

Site Status

Angers University Hospital

Angers, , France

Site Status

Besançon University Hospital

Besançon, , France

Site Status

Bordeaux University Hospital "Centre FX. Michelet"

Bordeaux, , France

Site Status

Brest University Hospital "Hôpital du Morvan"

Brest, , France

Site Status

Caen University Hospital "Hôpital de la Côte de Nacre"

Caen, , France

Site Status

Lille University Hospital "Hôpital Roger Salengro"

Lille, , France

Site Status

"Assistance Publique des Hôpitaux de Marseille - La Conception"

Marseille, , France

Site Status

Montpellier University Hospital "Hôpital Gui de Chauliac"

Montpellier, , France

Site Status

Mulhouse Hospital "Emile Muller"

Mulhouse, , France

Site Status

CHU Nantes

Nantes, , France

Site Status

"Institut de Cancérologie de Nice"

Nice, , France

Site Status

"Assistance Publique des Hôpitaux de Paris - Hôpital Bichat"

Paris, , France

Site Status

CHU Poitiers

Poitiers, , France

Site Status

Poitiers University Hospital

Poitiers, , France

Site Status

Rennes University Hospital "CHU Pontchaillou"

Rennes, , France

Site Status

Rennes University Hospital

Rennes, , France

Site Status

Rouen University Hospital

Rouen, , France

Site Status

Strasbourg University Hospital "Hôpital Hautepierre"

Strasbourg, , France

Site Status

"Institut Claudius Regaud"

Toulouse, , France

Site Status

"Pôle Santé Léonard de Vinci"

Tours, , France

Site Status

Pôle Santé Léonard de Vinci

Tours, , France

Site Status

Tours University Hospital

Tours, , France

Site Status

Countries

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France

Other Identifiers

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RC11_0147

Identifier Type: -

Identifier Source: org_study_id

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