Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol
NCT ID: NCT01531491
Last Updated: 2015-02-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
30 participants
INTERVENTIONAL
2012-01-31
2013-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DOUBLE
Study Groups
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Hypercapnia group
Respiratory rate will be 10/min and the rebreathing tube will be connected between the y-piece of corrugated tube and the tracheal tube to maintain the partial pressure of the end-tidal carbon dioxide at around 50 mmHg during emergence after propofol anesthesia.
Rebreathing tube
750 ml rebreathing tube will be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 50 mmHg.
Hypocapnia group
No rebreathing tube (Nothing) will be connected. Respiratory rate will be 10/min and the tidal volume will be modulated to maintain the partial pressure of the end-tidal carbon dioxide at around 30 mmHg during emergence after propofol anesthesia.
No rebreathing tube (Nothing)
750 ml rebreathing tube will not be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 30 mmHg.
Interventions
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Rebreathing tube
750 ml rebreathing tube will be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 50 mmHg.
No rebreathing tube (Nothing)
750 ml rebreathing tube will not be connected between the corrugated tube and the tracheal tube of a patient. Target partial pressure of the end-tidal carbon dioxide is 30 mmHg.
Eligibility Criteria
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Inclusion Criteria
* Age 20 - 60 years male and female
* Elective schedule with minor surgery under general anesthesia
Exclusion Criteria
* Patient with pulmonary, cardiac, endocrinal, neuromuscular and neurological diseases or past history
* Patient with medication affecting on this study
* Patient with general anesthesia history within one month
20 Years
60 Years
ALL
No
Sponsors
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DongGuk University
OTHER
Responsible Party
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Junyong In, MD
Associate professor
Principal Investigators
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Junyong In, M.D.
Role: PRINCIPAL_INVESTIGATOR
Department of anesthesiology and pain medicine, Dongguk University Ilsan Hospital
Locations
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Dept. of anesthesiology and pain medicine, Dongguk University Ilsan Hospital
Goyang, Kyunggido, South Korea
Countries
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Other Identifiers
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J In 2011-3
Identifier Type: -
Identifier Source: org_study_id
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