Impact of Whey and Soy Protein Ingestion in Conjunction With Energy Restriction in Overweight/Obese Individuals

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2013-05-31

Brief Summary

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It is known that dieting (restricted energy intake) without resistance training leads to a reduced metabolic rate, and the loss of both fat and muscle mass. When exercise is not included in a period of restricted energy intake, the degree to which muscle mass is lost is highly dependent upon protein consumption. Whey protein is a high quality protein isolated from milk and is known to stimulate new protein synthesis for all proteins in your body. Previous research has established that the consumption of whey protein has been correlated with retaining muscle mass while stimulating fat loss. However, the mechanisms behind these findings is still unknown. The purpose of this study is to establish a mechanistic underpinning to the efficacy of whey protein versus soy protein and a carbohydrate control (maltodextrin), in promoting fat mass loss and lean mass retention during a period of short-term controlled dietary energy deficit (-750 kcalories/day).

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Detailed Description

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Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Control

Carbohydrate \& 750 kcal dietary restriction while they receive a daily supplement (2 x 25 g) of maltodextrin (no protein) for 14 days. Weight loss.

Group Type PLACEBO_COMPARATOR

Weight loss

Intervention Type BEHAVIORAL

-750kcal/d

Whey

Whey protein \& 750 kcal dietary restriction while they receive a daily supplement (2 x 25 g) of WPI for 14 days. Weight loss.

Group Type EXPERIMENTAL

Weight loss

Intervention Type BEHAVIORAL

-750kcal/d

Whey

Intervention Type DIETARY_SUPPLEMENT

2 x 25g/d WPI

Soy

Soy protein \& 750 kcal dietary restriction while they receive a daily supplement (2 x 25 g) of SPC for 14 days. Weight loss.

Group Type EXPERIMENTAL

Weight loss

Intervention Type BEHAVIORAL

-750kcal/d

Soy

Intervention Type DIETARY_SUPPLEMENT

2 x 25g/d SPC

Interventions

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Weight loss

-750kcal/d

Intervention Type BEHAVIORAL

Soy

2 x 25g/d SPC

Intervention Type DIETARY_SUPPLEMENT

Whey

2 x 25g/d WPI

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Aged 35 to 55 years old
* Moderately Obese/Overweight (body mass index \> 25 and \< 42 kg/m2)
* Healthy
* Non-smoker

Exclusion Criteria

* Suffer from type 2 diabetes, hyperlipidemia, or thyroid dysfunction
* Taking medications
* Having an unstable weight in the past 4-6 months, or dieting at some time during the past 6 months
* Taking weight loss products or aids (including energy drinks)

Minimum Eligible Age

35 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes