Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-31

Study Completion Date

2012-10-31

Brief Summary

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Association of maternal uric acid with maternal condition and fetal outcome in pregnant women with hypertension.

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Detailed Description

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Association of maternal uric acid with maternal condition(renal function,liver function,...ect.) and fetal outcome(birth weight,APGER score) in pregnant women with hypertension.

Conditions

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Uric Acid and Hypertension in Pregnancy

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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A

40 pregnant Women with hypertension who have uric acid level more than 6 mg per dL.

measuring protein creatinin ratio,serum uric acid

Intervention Type OTHER

A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate.

Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method.

B

40 pregnant women with hypertension who have uric acid level less than 6 mg per dl.

measuring protein creatinin ratio,serum uric acid

Intervention Type OTHER

A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate.

Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method.

Interventions

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measuring protein creatinin ratio,serum uric acid

A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate.

Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age:18-40 years old
* Gestational age:28-42 weeks gestation singleton pregnancy of living fetus
* Non smoker

Exclusion Criteria

* women who refuse the study
* Any medical or obstetric disorders especially D.M.,renal disease,hepatic, cardiac disorders or gout arthritis, other than hypertension if present.
* Previously elevated uric acid level.
* Hemolytic or sickle cell anemia,urinary tract infection.
* Use of diuretics or anti-inflammatory drugs.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No