Placental Protein 13 Serum Endoglin and Uterine Doppler Indeces as Predictors of Pre-eclampsia

NCT ID: NCT02350036

Last Updated: 2017-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-31

Study Completion Date

2016-12-31

Brief Summary

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50 pregnant females were divided in two groups, twenty five as a control group and twenty five as high risk group; they were subjected to uterine artery Doppler, measurement of maternal serum and detection of (MTHFR) gene polymorphisms in first trimester at 11 to 14 weeks of gestation, all pregnancies were followed until 40 weeks for development of pre-eclampsia

Detailed Description

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50 pregnant females were divided in two groups, twenty five as a control group and twenty five as high risk group; they were subjected to uterine artery Doppler, measurement of maternal serum (pp-13) and detection of (MTHFR) gene polymorphisms in first trimester at 11 to 14 weeks of gestation, all pregnancies were followed until 40 weeks for development of pre-eclampsia

Conditions

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Preeclampsia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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preeclmapsia

women developed preeclampsia. ultrasound monitoring and uterine artery Doppler

ultrasound monitoring

Intervention Type OTHER

Uterine artery Doppler assessment

control

women with normal blood pressure all through pregnancy. ultrasound monitoring and uterine artery Doppler

ultrasound monitoring

Intervention Type OTHER

Uterine artery Doppler assessment

Interventions

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ultrasound monitoring

Uterine artery Doppler assessment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* pregnant women at 11 to 14 weeks of gestation

Exclusion Criteria

* fetal anomalies other medical diseases as diabetes mellitus, renal or liver diseases
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Maged

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed Maged

Role: PRINCIPAL_INVESTIGATOR

Kasr Alainy medical school

Locations

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Kasr Alainy medical school

Cairo, Cairo Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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125

Identifier Type: -

Identifier Source: org_study_id

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