LUCAS Chest Compressor Versus Manual Chest Compression in Out-of-hospital Sudden Cardiac Arrest. LUCAT Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2014-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this study is to show the superiority in survival at hospital admittance and in neurological outcome on hospital discharge of continuous mechanical chest compression using LUCAS device versus manual chest compressions in patients who suffered an out-of-hospital cardiac arrest.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pre-hospital ECMO or Conventional Resuscitation for Refractory Cardiac Arrest

NCT06177730

Out of Hospital Cardiac Arrest

NOT_YET_RECRUITING NA

Hemoadsorption With CytoSorb® in Post-Cardiac Arrest Syndrome

NCT03523039

Cardiac Arrest

COMPLETED NA

Neuromuscular Blockade for Post-Cardiac Arrest Care

NCT02260258

Cardiac Arrest

COMPLETED PHASE2

Hypertonic Lactate After Cardiac Arrest

NCT05004610

Cardiac Arrest Ischemia Reperfusion Injury Anoxic Brain Injury

RECRUITING PHASE2

COVID-19 Resuscitation Plans and Decisions on Escalation and Limitation of Treatment

NCT04743232

Covid19 Cardiac Arrest

SUSPENDED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The primary goals of the trial are:

* To show a survival increase at hospital admittance after out-of-hospital cardiac arrest of patients treated by continuous chest compressions LUCAS device compared with patients treated by manual chest compressions.
* To evaluate neurological outcome on hospital discharge, in two centres (Vall d'Hebron Hospital and Josep Trueta Hospital).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sudden Cardiac Arrest

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

LUCAS, Continuous chest compressions

Mechanical continuous chest compressions performed by LUCAS device (also during defibrillation)

Group Type ACTIVE_COMPARATOR

LUCAS (Lund University Cardiac Assist Sysrem)

Intervention Type DEVICE

LUCAS device will be placed on patients suffering a cardiac arrest and continuous chest compressions will be performed, even while defibrillation is being applied

Manual chest compressions

Manual chest compression is performed, chest compressions halted during defibrillation

Group Type ACTIVE_COMPARATOR

Manual chest compressions

Intervention Type OTHER

Manual CPR according to 2010 ERC guidelines will be performed

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

LUCAS (Lund University Cardiac Assist Sysrem)

LUCAS device will be placed on patients suffering a cardiac arrest and continuous chest compressions will be performed, even while defibrillation is being applied

Intervention Type DEVICE

Manual chest compressions

Manual CPR according to 2010 ERC guidelines will be performed

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Mechanical continuous chest compressions Cardiopulmonary resuscitation

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age: between 18 and 80 years ,
* Suffering from NON traumatic or an unexpected SCA,
* SCA witnessed (seen, heard or monitored),
* Attended by an advanced support ambulance (served by doctor or nurse) in Barcelona city, or in the Girona or Lleida area
* Time between alarm-call to SEM 061 and reaching patient is less than 12 minutes.

Exclusion Criteria

* Biological signs of death
* Age under 18 or over 80 years
* Trauma caused cardio respiratory arrest (CRA), including hanging
* Secondary CRA or intoxication
* Return of spontaneous circulation previous to arrival of SEM's medical team
* Known pregnancy
* Inadequate size for LUCAS device
* Anything in the study that can delay treatment

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No