Rehabilitation Robotics After a Stroke

NCT ID: NCT01383512

Last Updated: 2025-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

238 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2017-12-05

Brief Summary

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Upper limb motor control after a stroke may be improved with rehabilitation robotics at a subacute stage. The aim of this multicenter controled randomized single blind study is to define the place of rehabilitation robotics at this phase of the rehabilitation process. Both groups will realize the same time of rehabilitation. The cost benefit ratio will be compared in each group through medical assessment of improvement and definition of the costs due to the rehabilitation process.

Detailed Description

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Conditions

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Subacute Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Rehabilitation robotics

Subjects will be practicing an Armeo Spring rehabilitation program in addition to their usual care (1.5h/day,5d/week) 1h/day 5d/week 4 weeks.

Group Type EXPERIMENTAL

ARMEO Spring

Intervention Type DEVICE

Use of the device 1 hour per day, 5 days per week during 4 weeks

Self-rehabilitation

Subject will associated to there classical care 1 hours, 5 days per week during 4 weeks, of self rehabilitation.

Group Type ACTIVE_COMPARATOR

Self rehabilitation

Intervention Type OTHER

Subject have to realised alone rehabilitation exercises 1 hour per day, 5 days per week during 4 weeks.

Healthy volunteer

20 healthy volunteer will be recruiting and using ARMEO Spring. All volunteer will repeat 5 times the same program on the medical device.

Group Type OTHER

ARMEO Spring

Intervention Type DEVICE

Use of the device 1 hour per day, 5 days per week during 4 weeks

Interventions

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ARMEO Spring

Use of the device 1 hour per day, 5 days per week during 4 weeks

Intervention Type DEVICE

Self rehabilitation

Subject have to realised alone rehabilitation exercises 1 hour per day, 5 days per week during 4 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ischemic or hemorrhagic stroke of the middle cerebral arteria territory
* 18 to 80 years old
* stroke onset between 3 weeks to 3 months,with or without aphasia, with or without lateral neglect and homonymous hemianopia, with or without visual neglect
* 10\<or= Fugl Meyer upper limb Score \<or= 40
* upper limbs pain less or equal than 3/10 (VAS)
* inpatient or outpatient rehabilitation
* signed inform consent

Exclusion Criteria

* ischemic or hemorrhagic stroke of anterior or posterior cerebral artery
* ischemic or hemorrhagic stroke of the brainstem
* major aphasia evaluated by a Boston Diagnostic Aphasia Examination (BDAE) score less or equal to 3
* asthenia not allowing to work 60 minutes with the robot.
* serious visual deficiency not allowing to use the robot
* impossibility to install the arm on the robot because of a serious and uncontrolled spasticity or for any other reason
* pronounced and constant muscular contractures, or deformation affecting the use of the extremity
* upper limb's pain superior to 3/10 and/or being worse at the active and passive mobilization
* serious infection and/or instability of vital functions
* perfusion of the affected upper limb not removable
* incapacity to stay on a chair
* contraindicated sitting position
* permanent deviation of the head and\\or of the eyes
* perturbed or non-cooperative patient
* patients that must have to be isolated due to an infection process
* bone fracture of the paretic limb with an onset less than 3 months stabilized or not
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ministry of Health, France

OTHER_GOV

Sponsor Role collaborator

University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Olivier REMY-NERIS, Professor

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Brest

Locations

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CHU d'Amiens

Amiens, , France

Site Status

CRRRF

Angers, , France

Site Status

CHU de Bordeaux

Bordeaux, , France

Site Status

CHRU de Brest

Brest, , France

Site Status

Centre Bouffard Vercelli

Cervera de la Marenda, , France

Site Status

CHU de Clermont-Ferrand

Clermont-Ferrand, , France

Site Status

CHU de Dijon

Dijon, , France

Site Status

CH de Garches

Garches, , France

Site Status

EMPR Le Normandy

Granville, , France

Site Status

CHU de Nîmes

Le Grau-du-Roi, , France

Site Status

CHRU de Lille

Lille, , France

Site Status

CHU de Limoges

Limoges, , France

Site Status

CHU de Lyon

Lyon, , France

Site Status

CRF de Valmante

Marseille, , France

Site Status

CHU de Montpellier

Montpellier, , France

Site Status

IRR de Nancy

Nancy, , France

Site Status

CHU de Nantes

Nantes, , France

Site Status

APHP - Hôpital La Salpétriere

Paris, , France

Site Status

APHP - Hôpital Lariboisière

Paris, , France

Site Status

CMRRF Kerpape

Ploemeur, , France

Site Status

CHU de Reims

Reims, , France

Site Status

CHU de Rennes

Rennes, , France

Site Status

CHU de Toulouse

Toulouse, , France

Site Status

Countries

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France

References

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Cornec G, Lempereur M, Mensah-Gourmel J, Robertson J, Miramand L, Medee B, Bellaiche S, Gross R, Gracies JM, Remy-Neris O, Bayle N. Measurement properties of movement smoothness metrics for upper limb reaching movements in people with moderate to severe subacute stroke. J Neuroeng Rehabil. 2024 May 29;21(1):90. doi: 10.1186/s12984-024-01382-1.

Reference Type DERIVED
PMID: 38812037 (View on PubMed)

Remy-Neris O, Le Jeannic A, Dion A, Medee B, Nowak E, Poiroux E, Durand-Zaleski I; REM Investigative Team*. Additional, Mechanized Upper Limb Self-Rehabilitation in Patients With Subacute Stroke: The REM-AVC Randomized Trial. Stroke. 2021 Jun;52(6):1938-1947. doi: 10.1161/STROKEAHA.120.032545. Epub 2021 Apr 29.

Reference Type DERIVED
PMID: 33910364 (View on PubMed)

Other Identifiers

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REM_AVC

Identifier Type: -

Identifier Source: org_study_id

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