Myoelectric Robot-assisted Rehabilitation for the Upper Limb After Stroke

NCT ID: NCT02321254

Last Updated: 2017-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2016-04-30

Brief Summary

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The aim of this study is to assess the clinical effectiveness of the RehaARM-robot and to determine the feasibility of including robotic therapy in daily rehabilitation programmes, after stroke. Additionally, we aim to investigate the acceptance of this intervention from patients and therapists. A total of 10 patients will be recruited in this study, all the patients will receive 1 hour of standard therapy together with 45 min of robot therapy every day. The robot therapy will last 45 minutes, for 15 consecutive days within a maximum period of four weeks. Additional 15 minutes are required for placing surface electrodes on the shoulder and patient preparation. The study will include passive and active shoulder training of four movements: Horizontal abduction/adduction, abduction/adduction, internal/external rotation and flexion/extension. The passive part lasts 10 minutes and the active part 35 minutes.

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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The RehaARM-Robot

Receive 45 min of robot-assisted therapy for the shoulder and 1 hour of daily standard rehabilitation therapy.

Group Type EXPERIMENTAL

The RehaARM-Robot

Intervention Type DEVICE

Robot therapy by using a 3-Degrees-Of-Freedom (3DOFs) robot to train the shoulder.

Standard rehabilitation therapy

Intervention Type BEHAVIORAL

Standard therapy of stroke rehabilitation including speech, physical, occupational therapies and group activities.

Interventions

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The RehaARM-Robot

Robot therapy by using a 3-Degrees-Of-Freedom (3DOFs) robot to train the shoulder.

Intervention Type DEVICE

Standard rehabilitation therapy

Standard therapy of stroke rehabilitation including speech, physical, occupational therapies and group activities.

Intervention Type BEHAVIORAL

Other Intervention Names

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Robot-assisted therapy for the shoulder

Eligibility Criteria

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Inclusion Criteria

* Patients suffering from stroke, ischemic and / or hemorrhagic
* Stroke in the left hemisphere
* Score between 1 and 3 in the upper-limb sub-item of the Italian version of the National Institute of Health Stroke Scale (IT-NIHSS) (Pezzella et al. 2009)
* Score of the Functional Independence Measure (FIM) scale (Keith et al., 1987) less than 100 out of a total of 126. This scale is used as a reference to indicate the degree of autonomy in carrying out activities of daily living (ADLs)
* Score of the upper-limb Fugl-Meyer scale (FMA) (Fugl-Meyer et al., 1975) less than 60. This scale measures the residual motor function of a person after stroke

Exclusion Criteria

* Non-stabilized fractures
* Diagnosis of depression
* Traumatic brain Injury
* Pharmacologically uncontrolled epilepsy
* Ideomotor apraxia
* Neglect
* Mini Mental State Examination (MMSE) score \<20/30
* Severe impairment of verbal comprehension, defined by a score in the Token Test (Tau points\<58/78)
* Patients participating in other rehabilitation treatments for the upper-limb (e.g. virtual reality treatment, motor imagery, etc)
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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FerRobotics Compliant Robot GmbH, Linz, Austria

UNKNOWN

Sponsor Role collaborator

IRCCS San Camillo, Venezia, Italy

OTHER

Sponsor Role lead

Responsible Party

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Andrea Turolla

Head of Laboratory of Kinematics and Robotics

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andrea Turolla, MSc

Role: PRINCIPAL_INVESTIGATOR

IRCCS San Camillo Hospital Foundation, Venice (Italy)

Locations

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FerRobotics Compliant Robot Technology GmbH

Linz, , Austria

Site Status

IRCCS San Camillo Hospital Foundation

Venice, , Italy

Site Status

Countries

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Austria Italy

References

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Liao WW, Wu CY, Hsieh YW, Lin KC, Chang WY. Effects of robot-assisted upper limb rehabilitation on daily function and real-world arm activity in patients with chronic stroke: a randomized controlled trial. Clin Rehabil. 2012 Feb;26(2):111-20. doi: 10.1177/0269215511416383. Epub 2011 Aug 12.

Reference Type RESULT
PMID: 21840917 (View on PubMed)

Suputtitada A, Suwanwela NC, Tumvitee S. Effectiveness of constraint-induced movement therapy in chronic stroke patients. J Med Assoc Thai. 2004 Dec;87(12):1482-90.

Reference Type RESULT
PMID: 15822545 (View on PubMed)

Makowski NS, Knutson JS, Chae J, Crago PE. Functional electrical stimulation to augment poststroke reach and hand opening in the presence of voluntary effort: a pilot study. Neurorehabil Neural Repair. 2014 Mar-Apr;28(3):241-9. doi: 10.1177/1545968313505913. Epub 2013 Nov 22.

Reference Type RESULT
PMID: 24270058 (View on PubMed)

Mehrholz J, Hadrich A, Platz T, Kugler J, Pohl M. Electromechanical and robot-assisted arm training for improving generic activities of daily living, arm function, and arm muscle strength after stroke. Cochrane Database Syst Rev. 2012 Jun 13;(6):CD006876. doi: 10.1002/14651858.CD006876.pub3.

Reference Type RESULT
PMID: 22696362 (View on PubMed)

Laver KE, George S, Thomas S, Deutsch JE, Crotty M. Virtual reality for stroke rehabilitation. Cochrane Database Syst Rev. 2011 Sep 7;(9):CD008349. doi: 10.1002/14651858.CD008349.pub2.

Reference Type RESULT
PMID: 21901720 (View on PubMed)

Turolla A, Dam M, Ventura L, Tonin P, Agostini M, Zucconi C, Kiper P, Cagnin A, Piron L. Virtual reality for the rehabilitation of the upper limb motor function after stroke: a prospective controlled trial. J Neuroeng Rehabil. 2013 Aug 1;10:85. doi: 10.1186/1743-0003-10-85.

Reference Type RESULT
PMID: 23914733 (View on PubMed)

Kwakkel G, Kollen BJ, Krebs HI. Effects of robot-assisted therapy on upper limb recovery after stroke: a systematic review. Neurorehabil Neural Repair. 2008 Mar-Apr;22(2):111-21. doi: 10.1177/1545968307305457. Epub 2007 Sep 17.

Reference Type RESULT
PMID: 17876068 (View on PubMed)

Johansson BB. Current trends in stroke rehabilitation. A review with focus on brain plasticity. Acta Neurol Scand. 2011 Mar;123(3):147-59. doi: 10.1111/j.1600-0404.2010.01417.x. Epub 2010 Aug 19.

Reference Type RESULT
PMID: 20726844 (View on PubMed)

Hermens HJ, Freriks B, Disselhorst-Klug C, Rau G. Development of recommendations for SEMG sensors and sensor placement procedures. J Electromyogr Kinesiol. 2000 Oct;10(5):361-74. doi: 10.1016/s1050-6411(00)00027-4.

Reference Type RESULT
PMID: 11018445 (View on PubMed)

Sartori M, Reggiani M, Farina D, Lloyd DG. EMG-driven forward-dynamic estimation of muscle force and joint moment about multiple degrees of freedom in the human lower extremity. PLoS One. 2012;7(12):e52618. doi: 10.1371/journal.pone.0052618. Epub 2012 Dec 26.

Reference Type RESULT
PMID: 23300725 (View on PubMed)

Other Identifiers

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Prot.2013.16

Identifier Type: -

Identifier Source: org_study_id

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