Osteogenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling

NCT ID: NCT01323894

Last Updated: 2016-06-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2013-07-31

Brief Summary

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The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Detailed Description

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Our previous work is investigating the viral (Adv-BMP-2) administration for the development of a model to generate bones for possible use in clinical settings; the non-viral and viral administrations will be compared for best osteogenesis effects.

The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Conditions

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Primary Disease

Eligibility Criteria

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Inclusion Criteria

* age above 10 years old
* The patients require surgery ner iliac or abdomen areas

Exclusion Criteria

* age below 10 years old
Minimum Eligible Age

10 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China Medical University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sopha Chia-Ning Chang, M.D. Ph.D.

Role: PRINCIPAL_INVESTIGATOR

China Medical University Hospital

Locations

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China Medical Universty Hospital

Taichung, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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DMR-99-IRB-122

Identifier Type: -

Identifier Source: org_study_id

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