Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

NCT ID: NCT01296230

Last Updated: 2013-05-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

3 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-02-28

Study Completion Date

2017-02-28

Brief Summary

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The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.

Detailed Description

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Conditions

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Varicocele Infertility Semen Quality

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Hormone/semen measurements before and after varicocelectomy

We will measure sex-hormone and semen quality in patients both before and after varicocelectomy. The purpose is to asses if preoperative hormone levels are predictive for who will have improved semen quality after surgery.

Group Type EXPERIMENTAL

Hormone and semen measurements before varicocelectomy

Intervention Type PROCEDURE

Before surgery we will measure sex-hormone levels and semen parameters. This will be repeated after the varicocelectomy to record any changes.

Interventions

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Hormone and semen measurements before varicocelectomy

Before surgery we will measure sex-hormone levels and semen parameters. This will be repeated after the varicocelectomy to record any changes.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Varicocele (grade 1-3) and surgery planned for this condition
* At least 18 years of age

Exclusion Criteria

* Fever within 3 months before the first semen sample
* Malformations of the uro-genital tract
* Karyotype other than 46, XY or Y micro deletions
* Endocrine disease
* Chronic disease
* Medications which reduce semen quality
* Epididymitis within 6 months before surgery
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role collaborator

Copenhagen University Hospital at Herlev

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Department of Growth and Reproduction GR, Section 5064, Rigshospitalet

Copenhagen, , Denmark

Site Status

Department of Urology, Herlev Hospital

Herlev, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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H-2-2010-067

Identifier Type: -

Identifier Source: org_study_id

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