Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
28 participants
OBSERVATIONAL
2010-08-31
2012-12-31
Brief Summary
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Detailed Description
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The consequences of surgical stress response are numerous. Surgical stress response is essential to uneventful postoperative recovery. On the other hand, excessive surgical stress response may lead to serious postoperative complications, such as heart and kidney failure, venous thrombosis, disruption of operative wound and wound infection.
In prior studies the investigators have shown the kinetics of postoperative serum interleukin changes after radical resection of gastric cancer.
This study aims at determining reliable markers of surgical stress response severity in patients undergoing radical resection of colorectal cancer.
Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Colorectal cancer patients
Patients with pathohistologically verified colorectal cancer or adenoma with epithelial dysplasia
colorectal cancer resection
Open radical resection of colorectal cancer, according to oncological principals, depending on the tumor site
Interventions
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colorectal cancer resection
Open radical resection of colorectal cancer, according to oncological principals, depending on the tumor site
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* History of autoimmune diseases or immunodeficiencies
* Use of immunomodulatory drugs within 1 year prior to surgery
20 Years
90 Years
ALL
No
Sponsors
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University Hospital Dubrava
OTHER
Responsible Party
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Drazen Servis
M.D., Ph. D.
Principal Investigators
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Drazen Servis, M.D., Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University Hospital Dubrava
Locations
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University Hospital Dubrava
Zagreb, , Croatia
Countries
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References
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Servis D, Busic Z, Stipancic I, Patrlj L, Gagro A. Serum cytokine changes after gastric resection or gastrectomy for gastric cancer. Hepatogastroenterology. 2008 Sep-Oct;55(86-87):1868-72.
Etherek L, Servis D, Unic A. Soluble Triggering Receptor Expressed on Myeloid Cells-1 and Inflammatory Markers in Colorectal Cancer Surgery: A Prospective Cohort Study. Chin Med J (Engl). 2017 Nov 20;130(22):2691-2696. doi: 10.4103/0366-6999.218022.
Other Identifiers
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DS-P03112010
Identifier Type: -
Identifier Source: org_study_id
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