Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage

NCT ID: NCT02361918

Last Updated: 2015-02-12

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2012-03-31
• Study Completion Date: 2013-04-30

Brief Summary

Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.

Detailed Description

To search for a biomarker, which might be able to predict rectal anastomotic leakage before its clinical presentation. Serum procalcitonin, C-reactive protein, and drain fluid culture, IL-6 and TNF-α levels were evaluated in 50 consecutive patients with rectal cancer who underwent low anterior resection with colorectal anastomosis.

Conditions

Anastomotic Leakage in Colon Surgery

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

Anastomotic leakage

Patient had anastomotic leakage

Colon surgery

Intervention Type: PROCEDURE

No anastomotic leakage

Patient had no anastomotic leakage

Colon surgery

Intervention Type: PROCEDURE

Interventions

Colon surgery

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Patient underwent to colonic resection and had drain

Exclusion Criteria

• other patients

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Istanbul University

OTHER

Sponsor Role: lead

Responsible Party

Engin HATIPOGLU

M.D.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

CTF-EH0001

Identifier Type: -

Identifier Source: org_study_id