Hepatic Insulin Sensitivity and Very Low Density Lipoprotein Triglyceride (VLDL-TG) Kinetics
NCT ID: NCT01205750
Last Updated: 2011-06-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2010-03-31
2010-09-30
Brief Summary
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The primary objective of this study is to investigate VLDL-TG kinetics and hepatic insulin sensitivity in age-matched obese and lean, healthy men in the postabsorptive state and during acute hyperinsulinemia using VLDL-TG and glucose tracers.
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Detailed Description
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Conditions
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Study Design
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PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Glucose clamp
Glucose clamp
450 min hyperinsulinemic euglycemic glucose clamp, 0,5 mU / kg lean body mass / min
Interventions
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Glucose clamp
450 min hyperinsulinemic euglycemic glucose clamp, 0,5 mU / kg lean body mass / min
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* BMI \< 25 kg/m2 or \> 30 kg/m2
* Informed consent
Exclusion Criteria
* Smoking
* Use of prescription drugs
20 Years
50 Years
MALE
Yes
Sponsors
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University of Aarhus
OTHER
Responsible Party
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Medical department M (Endocrinology and Diabetes), Aarhus University Hospital, Denmark
Principal Investigators
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Søren Nielsen, DMSc
Role: PRINCIPAL_INVESTIGATOR
Medical department M (Endocrinology and Diabetes), Aarhus University Hospital, Denmark
Locations
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Department of Endocrinology and Internal Medicine, Aarhus University Hospital
Aarhus, , Denmark
Countries
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Other Identifiers
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2009-0132
Identifier Type: -
Identifier Source: org_study_id
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