Studies Examining the Importance of Smoking After Being Diagnosed With Lung Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

2400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-03-31

Study Completion Date

2021-03-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A large project consisting of:

a) an observational trial where smoking status is recorded on 1400 consecutive people newly diagnosed with lung cancer. Smoking status is biologically validated with exhaled carbon monoxide (eCO) levels every 3 months. Survival, cancer progression and treatment complications will be recorded and compared in smokers, ex-smokers and never smokers.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK

NCT06575439

Lung Cancer

RECRUITING

Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.

NCT06016569

Lung Cancer

RECRUITING NA

Understanding Non-small Cell Lung Cancer Patient Characteristics, Treatment Patterns and Outcomes

NCT07215026

Non-small Cell Lung Cancer

ENROLLING_BY_INVITATION

Metabolic and Microbial Profiling of Lung Cancer

NCT03998189

Nonsmall Cell Lung Cancer Nonsmall Cell Lung Cancer Stage

TERMINATED NA

S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

NCT00450281

Lung Cancer

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Smoking causes around 85% of lung cancer. Continued smoking after diagnosis probably worsens survival and increases treatment complications but prospective well-designed studies are lacking.

This project is an observational cohort study recording outcomes in smokers, never-smokers, and ex-smokers, using exhaled carbon monoxide to validate smoking status when they attend for further lung cancer clinics.

This project is unique, as every patient with a clinical diagnosis of lung cancer will have their smoking status biologically validated by a quick and easy test, and those enrolled in the smoking cessation treatments or not will also complete a generic quality of life questionnaire at regular intervals. These appointments will coincide with other hospital appointments wherever possible, and survival status will reported up to 24 months after enrolment.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Lung Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* clinical diagnosis of lung cancer

Exclusion Criteria

* refusal Consent
* inability to provide exhaled CO
* active psychiatric illness or substance misuse
* concurrent malignancies of another type other than non-melanoma skin cancer
* unable to travel for sessions with smoking cessation counsellor and / or outpatient visits from outset
* WHO performance status 4
* Life expectancy less than 6 weeks.

Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No