Breath Analysis to Diagnose Lung Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1500 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-29

Study Completion Date

2024-04-29

Brief Summary

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Determination of volatile organic compounds to discriminate patients with lung cancer from healthy smokers and non-smokers healthy subjects.

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Detailed Description

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Conditions

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Lung Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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patients

Patients with bronchopulmonary cancer who have not yet received therapeutic treatment.

Group Type EXPERIMENTAL

Collection of volatile organic compounds during exhalation

Intervention Type DEVICE

The volatile organic compounds (VOCs) are collected in sorbents at rest and at the end of exhalation according to the concentration of carbon dioxide using ReCIVA breath sampler.

The identification of the VOCs will be done by chromatography (Gas Chromatography Mass Spectrometry GC-MS)

controls

The controls consisted of 2 groups: smokers and non-smokers.

Group Type ACTIVE_COMPARATOR

Collection of volatile organic compounds during exhalation

Intervention Type DEVICE

The volatile organic compounds (VOCs) are collected in sorbents at rest and at the end of exhalation according to the concentration of carbon dioxide using ReCIVA breath sampler.

The identification of the VOCs will be done by chromatography (Gas Chromatography Mass Spectrometry GC-MS)

Interventions

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Collection of volatile organic compounds during exhalation

The volatile organic compounds (VOCs) are collected in sorbents at rest and at the end of exhalation according to the concentration of carbon dioxide using ReCIVA breath sampler.

The identification of the VOCs will be done by chromatography (Gas Chromatography Mass Spectrometry GC-MS)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* patients with histologically proven lung cancer

Controls:

* healthy smoker or non-smoker subjects
* without respiratory diseases excepted chronic obstructive pulmonary disease.

Exclusion Criteria

* history of cancer other than lung cancer within 5 years before inclusion
* oral or facial malformation
* incomprehension of maneuvers for the collection

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No