Comparison of Longer-term (5 Year+) Outcomes (Survival) of Smokers, Ex-smokers, Never Smoker and Quitters

NCT ID: NCT07127263

Last Updated: 2025-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

525 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-05

Study Completion Date

2025-05-30

Brief Summary

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Between 2010-2020, the LungCAst observational study followed 3700 patients newly diagnosed with lung cancer across 33 hospitals in Wales and England for 2 years to see if smoking status at time of diagnosis predicted survival rate. This research was sponsored and led by Hywel Dda University Health Board (HDUHB).

This new study examines the health records, (of only the HDUHB participants included in the original LungCAst study), over a longer period of time to see if the benefits of stopping smoking at point of diagnosis with lung cancer continues over a longer period of time (5 years+).

Detailed Description

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A study into longer-term outcomes from the LUNGCAST study: comparing survival and healthcare utilisation according to smoking status in people with lung cancer, beyond 2 years. By obtaining Hospital Episode Statistics (HES) extract from the Welsh Patient Administration System (WPAS) and Welsh Clinical Portal (WCP) the investigators can retrospectively follow the cohort participants over time and analyse health care utilisation activity, using univariate and multivariate analysis on the effect of smoking status on survival. The Kaplan-Meier method, will be used to estimate the probability of survival over time.

Conditions

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Lung Cancer - Non Small Cell Squamous

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Diagnosed Lung Cancer

Patients diagnosed with Lung Cancer, with smoking status recorded at time of diagnosis.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

All patients from the Hywel Dda University Health Board's(HDUHB) site that participated in the original LungCast study

Exclusion Criteria

* Individuals that did not participate in the original LungCast study in the HDUHB site.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hywel Dda Health Board

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hywel Dda University Health Board

Carmarthen, Carmarthenshire, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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IRAS 339817

Identifier Type: -

Identifier Source: org_study_id

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