Prevalence of COPD in Our Lung Cancer Population, Compared to Controls

NCT ID: NCT02603627

Last Updated: 2015-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Brief Summary

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This study will investigate the prevalence of chronic obstructive pulmonary disease (COPD) in patients who are newly diagnosed with lung cancer and compare it to the prevalence of COPD in controls recruited from a smoking cessation clinic.

Detailed Description

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Chronic obstructive pulmonary disease (COPD) is a breathing problem that some people develop. Usually it is caused by smoking. Damage to the lungs means that patients are at risk of more chest infections and are unable to exercise like healthy individuals. They may also have a long-standing cough.

COPD is diagnosed by testing lung function, usually using a small device called a spirometer.

COPD is becoming a better understood condition. It is known that the lungs of patients with COPD are sometimes inflamed. This is important because inflammation is associated with some types of cancer, including lung cancer.

The investigators are interested in whether COPD puts people at higher risk of lung cancer. They would like to find out how common COPD is in patients who have lung cancer. The investigators would also like to find out how common COPD is in patients who are not known to have lung cancer (comparison group). This will help them interpret their results better as investigators will be able to compare the two groups.

Conditions

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COPD Lung Cancer Smoking

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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With lung cancer

Patients who have a new diagnosis of lung cancer will be invited to undergo spirometry to enable us to gather data on the prevalence of COPD in this group.

No interventions assigned to this group

Without lung cancer

Smokers who are referred to the smoking cessation clinic will be invited to undergo spirometry to ascertain the prevalence of COPD in this group.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Informed consent
* Aged over 18
* Lung cancer group: new diagnosis of lung cancer, with spirometry results available Control group: spirometry result available or obtained

Exclusion Criteria

* Patient refusal
* Age under 18
* Control group: pre-existing lung cancer
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Guy's and St Thomas' NHS Foundation Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tariq Sethi, MBBS PhD

Role: PRINCIPAL_INVESTIGATOR

King's Health Partners

Anthony Dorr, MBBS PhD

Role: PRINCIPAL_INVESTIGATOR

Guy's and St Thomas' NHS Foundation Trust

Locations

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Guy's and St Thomas' NHS Foundation Trust

London, England, United Kingdom

Site Status

Countries

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United Kingdom

Central Contacts

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Alex Cumberworth, BM BS BSc

Role: CONTACT

Facility Contacts

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Tariq Sethi, MBBS PhD

Role: primary

02032993165

Other Identifiers

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15/YH/0091

Identifier Type: OTHER

Identifier Source: secondary_id

RJ115/N106

Identifier Type: -

Identifier Source: org_study_id

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