The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Study Classification

INTERVENTIONAL

Study Start Date

2010-07-31

Study Completion Date

2010-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Aim: eliminating or reducing pain following endodontic treatment is of great importance. The aim of this study is to compare the effects of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis. Sample size: one hundred patients considering the inclusion and exclusion criteria were selected. Intervention and outcome: The effect of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root canals in teeth with irreversible pulpitis was evaluated.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Oral Analgesics on Post-op Pain

NCT07204379

Post Operative Pain

COMPLETED EARLY_PHASE1

Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain

NCT05982392

Symptomatic Irreversible Pulpitis Post Operative Pain

COMPLETED PHASE2/PHASE3

Efficacy of Different Drugs to Control Post Root Canal Treatment Pain

NCT02417337

Pain Postoperative Pain Irreversible Pulpitis

COMPLETED PHASE2

Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIP

NCT07036237

Post-endodontic Pain

ENROLLING_BY_INVITATION NA

Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis

NCT04961268

Symptomatic Irreversible Pulpitis

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pulpitis Pain Management

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Placebo

Intervention Type DRUG

Tramadol

Tab, 100mg in 6, 12 and 24 hours after root canal treatment

Intervention Type DRUG

Novafen

325 mg in 6, 12 and 24 hours after root canal treatment

Intervention Type DRUG

Naproxen

Tab, 500 mg in 6, 12, and 24 hours after root canal treatment

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. The subjects were 20-60 years of age with no systemic diseases and females were not pregnant;
2. No history of taking any analgesics or other drugs prior to presenting for treatment;
3. Patients had moderate to severe pain associated with irreversible pulpitis in single-rooted premolars or anterior teeth.

Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No