Nutritional Quality of Egg Proteins and Effect on Satiety

NCT ID: NCT01154582

Last Updated: 2025-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

43 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-02-28

Brief Summary

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The project aims to precisely quantify the postprandial amino acid utilization of egg proteins in vivo in humans, and also to assess their satiating power, in relation with nutrient postprandial waves and incretin secretions. For that purpose, 2 independent studies are conducted. The first one is realized using stable isotopes on 8 volunteers ingesting an egg test meal. The second one is a cross over design performed on 30 volunteers to compare the satiating effect of 2 equivalent snacks: whole eggs or cottage cheese.

Detailed Description

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Conditions

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Physiology Nutrition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Study Groups

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Egg

Group Type EXPERIMENTAL

Egg snack

Intervention Type DIETARY_SUPPLEMENT

subject consume 4 cooked whole eggs, providing 380 kcal

Cottage cheese

Group Type EXPERIMENTAL

Cottage cheese

Intervention Type DIETARY_SUPPLEMENT

Subjects consume 200 g of cottage cheese, providing 380 kcal

Interventions

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Egg snack

subject consume 4 cooked whole eggs, providing 380 kcal

Intervention Type DIETARY_SUPPLEMENT

Cottage cheese

Subjects consume 200 g of cottage cheese, providing 380 kcal

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy volunteers
* BMI between 18 and 25

Exclusion Criteria

* Allergy to egg or milk protein
* Digestive or metabolic pathology
* Positiveness to HIV, Hepatitis B and C
* Smokers
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Research Agency, France

OTHER

Sponsor Role collaborator

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre de recherche sur volontaires

Bobigny, , France

Site Status

Centre de recherche sur Volontaires

Nantes, , France

Site Status

Countries

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France

References

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Fromentin C, Tome D, Nau F, Flet L, Luengo C, Azzout-Marniche D, Sanders P, Fromentin G, Gaudichon C. Dietary proteins contribute little to glucose production, even under optimal gluconeogenic conditions in healthy humans. Diabetes. 2013 May;62(5):1435-42. doi: 10.2337/db12-1208. Epub 2012 Dec 28.

Reference Type DERIVED
PMID: 23274906 (View on PubMed)

Other Identifiers

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OVONUTRIAL

Identifier Type: -

Identifier Source: org_study_id

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