Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
224 participants
INTERVENTIONAL
2010-03-31
2011-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Reason to Season; Flavors to Increase Vascular Health
NCT04339114
Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)
NCT00954902
Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health
NCT06363305
Effects of Tomato Sauce on Endothelial Dysfunction Induced by a High Fat Meal in Healthy Subjects
NCT01968369
Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
NCT04530916
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Dietary supplement: Cinnamon
Cinnamon
2.8g/day of cinnamon in capsules during 4 weeks.
Dietary supplement: Oregano
Oregano
2.8g/day of oregano in capsules during 4 weeks.
Dietary supplement: Ginger
Ginger
2.8g/day of ginger in capsules during 4 weeks.
Dietary supplement: Rosemary
Rosemary
2.8g/day of rosemary in capsules during 4 weeks.
Dietary supplement: Black pepper
Black pepper
2.8g/day of black pepper in capsules for 4 weeks.
Dietary supplement: Placebo
Placebo
2.8 g/day of placebo in capsules (corn starch) during 4 weeks.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Cinnamon
2.8g/day of cinnamon in capsules during 4 weeks.
Oregano
2.8g/day of oregano in capsules during 4 weeks.
Ginger
2.8g/day of ginger in capsules during 4 weeks.
Rosemary
2.8g/day of rosemary in capsules during 4 weeks.
Black pepper
2.8g/day of black pepper in capsules for 4 weeks.
Placebo
2.8 g/day of placebo in capsules (corn starch) during 4 weeks.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Men and postmenopausal women
* Waist girth \>102cm (men) or \>88cm (women)
* LDL-C \> 2.8 mmol/L
* Framingham 10-yr risk score \< 10%
* Marginal endothelial dysfunction
* Non smoker
Exclusion Criteria
* History of CVD, diabetes, other endocrines disorders
* Pre-menopausal women
* Alcohol consumption \> 1 drink per day
* Unusual dietary habits (e.g. vegetarism)
* Chronic use of supplements (estrogens, vitamins, minerals or flavonoids)
* Aversion or intolerance for spices and/or herbs
* Injury to fingers or amrs that would interfere with endothelial function measurement
40 Years
70 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
McCormick Canada Co
UNKNOWN
Laval University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Charles Couillard
Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Charles Couillard, Ph.D
Role: PRINCIPAL_INVESTIGATOR
Laval University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Richardson Centre of Functional Foods and Nutracuticals
Winnipeg, Manitoba, Canada
Institute of Nutraceuticals and Functional Foods
Québec, Quebec, Canada
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Carnovale V, Paradis ME, Gigleux I, Ramprasath VR, Couture P, Jones PJ, Lamarche B, Couillard C. Correlates of reactive hyperemic index in men and postmenopausal women. Vasc Med. 2013 Dec;18(6):340-6. doi: 10.1177/1358863X13507975.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
INAF-2009-253
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.