Effects of Peppermint Oil in Cardiometabolic Outcomes

NCT ID: NCT05071833

Last Updated: 2023-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2022-11-05

Brief Summary

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Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount. Dietary interventions to improve cardiometabolic health are highly sought after as they possess less risk than pharmacological drugs. Previous non-randomized interventions have shown that oral peppermint may be beneficial in improving cardiometabolic outcomes. However, to date, no research has explored this using a placebo randomized intervention.

Therefore, the primary purpose of the proposed investigation is to test the ability of oral peppermint oil supplementation to improve cardiometabolic parameters in healthy individuals.

Detailed Description

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Conditions

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Cardiometabolic Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Placebo

Identical in taste and colour to the supplement juice, but with no peppermint content.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Placebo

Peppermint oil

50 uL of peppermint oil, which will be diluted with 100 mL of water - taken twice per day.

Group Type EXPERIMENTAL

Peppermint oil.

Intervention Type DIETARY_SUPPLEMENT

Peppermint oil.

Interventions

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Peppermint oil.

Peppermint oil.

Intervention Type DIETARY_SUPPLEMENT

Placebo

Placebo

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Between 18 \& 65 years
* Non-smoker
* BMI \< 30
* Able to give informed consent

Exclusion Criteria

* Pregnancy
* Diabetes or any other metabolic/ uncontrolled hypertensive conditions
* Food allergies to peppermint
* Habitual consumption of peppermint
* Not regularly taking medication or antioxidant supplements
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Central Lancashire

OTHER

Sponsor Role lead

Responsible Party

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Jonathan Sinclair

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Jonathan Sinclair

Preston, Lancashire, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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Peppermint oil cardiometabolic

Identifier Type: -

Identifier Source: org_study_id

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