Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
155 participants
INTERVENTIONAL
2017-02-17
2017-09-18
Brief Summary
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Detailed Description
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The current randomised, placebo controlled, parallel groups study extends on the abovementioned small amount of literature; assessing both cognitive and mood outcomes in a sample of older (50-70 yrs) adults, as well as blood pressure (BP) and CBF, in a sub-sample, utilizing near-infrared spectroscopy (NIRS). The above will be assessed acutely (pre-dose and 90- and 310-mins post dose) on day 1 and following 28 days consumption of either a placebo control, and active control of 240 mg ginkgo biloba, 475 mg SS or 950 mg SS.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
TRIPLE
Study Groups
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Placebo control
Inert comparator indistinguishable from active interventions
Placebo control
An inert encapsulated powder provided by Finzelberg.
Active control
240 mg ginkgo biloba
Ginkgo biloba
Ginkgo biloba is an extract from the ginkgo tree comprising ginkgolides and bilobalide. In this trial Ginkgo acted as an active control.
Low dose sideritis scardica
475 mg sideritis scardica
Sideritis Scardica
Sideritis Scardica is a popular, naturally un-caffeinated Eastern European tea extract derived from the ironwort plant
High dose sideritis scardica
950 mg sideritis scardica
Sideritis Scardica
Sideritis Scardica is a popular, naturally un-caffeinated Eastern European tea extract derived from the ironwort plant
Interventions
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Sideritis Scardica
Sideritis Scardica is a popular, naturally un-caffeinated Eastern European tea extract derived from the ironwort plant
Ginkgo biloba
Ginkgo biloba is an extract from the ginkgo tree comprising ginkgolides and bilobalide. In this trial Ginkgo acted as an active control.
Placebo control
An inert encapsulated powder provided by Finzelberg.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* No underlying health problem which would prevent engagement with the study
Exclusion Criteria
* High blood pressure (defined as systolic \> 159 mmHg or diastolic \> 90 mmHg)
* Smoking
* Food allergies or insensitivities
* Pregnancy or breast feeding
* Currently taking any medication (use of contraceptives/hormone replacements was not excluded) or dietary supplements which would contraindicate with the study
* Sleep disturbances and/or taking sleep aid medication
* History of neurological, vascular or psychiatric illness
* Current diagnosis of anxiety or depression
* Migraines
* Recent history (within 12 months) of alcohol/substance abuse
* Disorder of the blood
* Heart disorder/history of vascular illness
* Respiratory disorder requiring regular medication
* Type I or II diabetes
* Renal disease, hepatic disease or severe disease of the gastrointestinal tract - Any health condition that would prevent the fulfilment of the study requirements
50 Years
70 Years
ALL
Yes
Sponsors
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Finzelberg
UNKNOWN
Northumbria University
OTHER
Responsible Party
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Emma Wightman
Principal investigator
Principal Investigators
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Emma L Wightman, PhD
Role: PRINCIPAL_INVESTIGATOR
Northumbria University
Locations
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Brain Performance and Nutrition Research centre
Newcastle upon Tyne, Tyne and Wear, United Kingdom
Countries
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Other Identifiers
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SUB010_Khan_141116
Identifier Type: -
Identifier Source: org_study_id
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